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- Many of the infected cells fall off the bladder's surface into the urine, but IBCs also release bacteria, many of which have a long, slender filamentous appearance (E. coli usually have a simple rod-like shape).
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Aug 19, 2020 · These bacteria undertake a multistage infection cycle involving invasion of and proliferation within urinary tract epithelial cells, leading to the rupture of the host cell and dispersal of the bacteria, some of which have a highly filamentous morphology.
Jan 1, 2008 · E. coli is Gram-negative and its envelope has three layers: cytoplasmic membrane, peptidoglycan, and outer membrane. The peptidoglycan is rigid determining the rod shape. To a good approximation, the E. coli cell has hemispherical caps and a cylindrical section in between.
- Galina Reshes, Sharon Vanounou, Itzhak Fishov, Mario Feingold
- 10.1529/biophysj.107.104398
- 2008
- Biophys J. 2008 Jan 1; 94(1): 251-264.
Jan 11, 2022 · Article. Open access. Published: 11 January 2022. Transcriptional alterations in bladder epithelial cells in response to infection with different morphological states of uropathogenic...
- Katarina Persson
Jul 12, 2017 · Urinary tract infections (UTIs) are the commonest human bacterial infections and are responsible for substantial morbidity and mortality, resulting in increased healthcare costs. Most UTIs are caused by specialized Escherichia coli (E. coli) strains referred to as uropathogenic E. coli (UPEC). UPEC possess a variety of virulence factors (VFs), which the organism uses to attach, invade, and ...
- Timothy Kudinha
- 2017
May 16, 2024 · Using a synthetic reporter of cell division, we follow the temporal dynamics of cell division for different E. coli clinical strains in a UTI mouse model with and without antibiotics. We show that more bacteria are actively dividing in the kidneys and urine compared with the bladder.
Jan 1, 2014 · Abstract. Escherichia coli is a non-spore-forming, Gram-negative bacterium, usually motile by peritrichous flagella. Escherichia coli is the most common cause of acute urinary tract infections as well as urinary tract sepsis. It has also been known to cause neonatal meningitis and sepsis and also abscesses in a number of organ systems.
