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      • Evidence has supported the predictive value of gestational age, maternal intraamniotic infection (represented either by intrapartum fever or the obstetric clinical diagnosis of chorioamnionitis), the duration of rupture of membranes (ROM), maternal GBS colonization, the administration of appropriate intrapartum antibiotic therapy, and the newborn clinical condition. 2,14,–16 Surveillance studies in the United States reveal higher rates of EOS among infants who are born to mothers of African...
      publications.aap.org › pediatrics › article

      Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With ...

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  3. publications.aap.org › pediatrics › articleEarly-Onset Sepsis Among Very Preterm Infants | Pediatrics ...

    Oct 1, 2021 · Very preterm infants with early-onset sepsis had higher adjusted risks of death and major medical morbidity compared with those uninfected. Early-onset sepsis (EOS) is a significant cause of morbidity and mortality among newborn infants.

    • Dustin D. Flannery, Dustin D. Flannery, Erika M. Edwards, Karen M. Puopolo, Karen M. Puopolo, Jeffre...
    • 2021

  4. publications.aap.org › pediatrics › articleManagement of Neonates Born at ≥35 0/7 Weeks’ Gestation With ...

    Dec 1, 2018 · Combining immature and total neutrophil counts to predict early onset sepsis in term and late preterm newborns: use of the I/T 2.

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018

  5. publications.aap.org › pediatricsinreview › articleEarly-Onset Sepsis in Newborns | Pediatrics In Review ...

    Jan 1, 2023 · Early-onset sepsis can cause significant morbidity and mortality in newborn infants. Risk factors for sepsis include birth to mothers with.

  6. www.uptodate.com › contents › clinical-featuresClinical features, evaluation, and diagnosis of sepsis in ...

    Oct 18, 2023 · Although the incidence of sepsis in term and late preterm neonates is low, the potential for serious adverse outcomes is of such great consequence that caregivers should have a low threshold for evaluation and treatment for possible sepsis in neonates.

  7. www.ncbi.nlm.nih.gov › books › NBK531478Neonatal Sepsis - StatPearls - NCBI Bookshelf

    Sep 29, 2022 · Early-onset sepsis (EOS) is generally caused by the transmission of pathogens from the female genitourinary system to the newborn or the fetus. These pathogens can ascend the vagina, the cervix, and the uterus, and can also infect the amniotic fluid.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29

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  9. www.ncbi.nlm.nih.gov › pmc › articlesUpdates in Late-Onset Sepsis: Risk Assessment, Therapy and ...

    Nov 11, 2022 · Neonatal late-onset sepsis (LOS) remains a significant cause of morbidity and mortality in the NICU, particularly among extremely preterm and/or chronically ill infants. Early recognition and diagnosis of LOS is challenging due to often non-specific presenting features and limited diagnostic efficiency of commonly used biomarkers.

  10. www.ncbi.nlm.nih.gov › pmc › articlesEarly neonatal sepsis: prevalence, complications and outcomes ...

    Oct 4, 2021 · Nowadays, the incidence of ENS in infants born at term is of approximately 0.5/1,000 live births; this number doubles among late preterm newborns (PTNB), and is even more significant in PTNB<34 weeks, and NB with very low birth weight. 4