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1. • • The treatment plan is aimed at fluid rehydration continuation, overcoming infection and sepsis with antibiotics and source control; management of KAD with administration of fluids, insulin, and electrolyte correction.
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     Management of Sepsis Patient Aggravated by Diabetic Ketoacidosis

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   What happens if a diabetic gets a sepsis?

   • An infection occurs when germs enter a person’s body and multiply, causing illness, organ and tissue damage, or disease. For people with diabetes, an infection can turn serious, or even deadly, very fast. Sepsis is the body’s overwhelming and life-threatening re-sponse to infection, which can lead to tissue damage, organ failure, and death.

   SEPSIS AND DIABETES

   www.sepsis.org/wp-content/uploads/2021/03/Sepsis-Diabetes-2021.pdf

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   Can a diabetic patient get a sepsis if he has T2D?

   • Patients with T2D have an increased risk of developing infections and sepsis. Although a few rare infections such as Klebsiella liver abscesses, malignant otitis externa, and emphysematous cholecystitis are strongly associated with diabetic patients, most infections that occur in diabetics are also common in the general population ( 23 ).

   Diabetes and Sepsis: Risk, Recurrence, and Ruination - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC5670360/

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   Do diabetic patients with severe sepsis fare worse than non-diabetic patients?

   • Chang C-W, Kok VC, Tseng T-C, Horng J-T, Liu C-E. Diabetic patients with severe sepsis admitted to intensive care unit do not fare worse than non-diabetic patients: a nationwide population-based cohort study. PLoS ONE. 2012;7:e50729. [ PMC free article] [ PubMed] [ Google Scholar]

   Impact of diabetes mellitus on outcomes of patients with sepsis: an

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8898404/

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3. www.ncbi.nlm.nih.gov › pmc › articlesType 2 diabetes mellitus and sepsis: state of the art,...

   www.ncbi.nlm.nih.gov › pmc › articles

   May 10, 2021 · This work aims at reviewing the current state of knowledge about: (1) the impact of diabetes and sepsis on the immune system, (2) the influence of diabetes on the risk of sepsis and its outcomes, and (3) the optimal target for blood glucose control during sepsis in patients with diabetes.

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     Lower overall ICU mortality (8.0% vs. 4.6%, p < 0.04) due to...

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     A better understanding of the underlying diabetic-induced...

4. www.ncbi.nlm.nih.gov › pmc › articlesDiabetes and Sepsis: Risk, Recurrence, and Ruination - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 30, 2017 · A better understanding of the underlying diabetic-induced immune cell defects that persist following sepsis are crucial to identify potential therapeutic targets to bolster innate and adaptive immune function, prevent infectious complications, and provide more durable diabetic survival.

   • Author: Lynn M. Frydrych, Fatemeh Fattahi, Katherine He, Peter A. Ward, Matthew J. Delano

   • Publish Year: 2017

5. journals.lww.com › shockjournal › FulltextDiabetes Mellitus and Sepsis: A Challenging Association - LWW

   journals.lww.com › shockjournal › Fulltext

   Jul 27, 2016 · Scheme depicting the immune response of patients with diabetes mellitus during sepsis.During early sepsis, patients with T1D have defective neutrophil functions (chemotaxis, phagocytosis, and killing), resulting in impaired bacterial control at the site of infection, bacteremia and a poor sepsis outcome.

6. www.sepsis.org › 2021 › 03SEPSIS AND DIABETES - Sepsis Alliance

   www.sepsis.org › 2021 › 03

   An infection occurs when germs enter a person’s body and multiply, causing illness, organ and tissue damage, or disease. For people with diabetes, an infection can turn serious, or even deadly, very fast. Sepsis is the body’s overwhelming and life-threatening re- sponse to infection, which can lead to tissue damage, organ failure, and death.

7. www.sepsis.org › news › the-connection-betweenThe Connection Between Diabetes and Sepsis | Sepsis Alliance

   www.sepsis.org › news › the-connection-between

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   Oct 31, 2019 · If you have an infection or suspect you may have one, remember the memory aid TIME™ and seek immediate medical help if you think you may have sepsis. Suspect sepsis. Save lives. Having diabetes can lower a person ability to fight infections, and any infection can lead to sepsis.

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9. www.sepsis.org › news › diabetes-and-why-itDiabetes and Why It Increases Sepsis Risk | Sepsis Alliance

   www.sepsis.org › news › diabetes-and-why-it

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   Mar 20, 2019 · Diabetes has no cure. It can be managed, keeping blood sugar levels as close to normal ranges as possible, but it takes work to do so. Consistently high blood sugar levels or wildly fluctuating levels cause damage to your body, from the blood vessels to the organs.

10. www.ncbi.nlm.nih.gov › pmc › articlesImpact of diabetes mellitus on outcomes of patients with ...

    www.ncbi.nlm.nih.gov › pmc › articles

    Mar 5, 2022 · Conclusions. Diabetes is not associated with poor survival outcomes in patients with sepsis but is associated with increased risk of acute renal failure. High blood glucose levels, irrespective of the diabetes status, are associated with increased risk of in-hospital mortality.