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Enterobacteria phage λ (lambda phage, coliphage λ) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli. This virus is temperate and may reside within the genome of its host through lysogeny.
Searches related to lambda bacteriophage vector
Lambda phage will enter bacteria more easily than plasmids, making it a useful vector that can either destroy or become part of the host's DNA. [31] Lambda phage can also be manipulated and used as an anti-cancer vaccine that targets human aspartyl (asparaginyl) β-hydroxylase (ASPH, HAAH), which has been shown to be beneficial in cases of ...
Aug 3, 2023 · The lambda phage is a typical example of bacteriophage which has a polyhedral head and tail. The DNA is protected by the polyhedral structure, and the tail interacts with the specific site of bacteria for attachment.
- Somak Banerjee
Its cloning relied on the confluence of microbial genetics in the form of the groE mutants isolated by Costa Georgopoulos, and one of the earliest recombinant DNA techniques in the form of a shotgun (random) library of E. coli DNA fragments in a phage lambda vector.
- Sherwood R. Casjens, Roger W. Hendrix
- 10.1016/j.virol.2015.02.010
- 2015
- 2015/05
Some lambda vectors have been designed to be readily converted into plasmids or phagemids, and there are a variety of promoters and fusions that can be used to drive expression of foreign genes. Screening lambda libraries with antibodies or ligands is a powerful way of identifying novel genes.
- Alan C. Christensen
- 2001
May 17, 2024 · Bacteriophage lambda, a member of the Siphovir uses with a long and flexible tail, has served as a crucial model for bacteriophage biology and genetics since its discovery in the 1950s 1,...
Jan 1, 1988 · Bacteriophage lambda is the most studied and best characterized of all the bacterial extrachromosomal elements. Over the past 20 years, lambda has served as model system for the study of bacteriophage morphogenesis, DNA replication, and gene regulation. It also serves as one of the first molecular cloning vectors.
