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  1. Jan 18, 2022 · Generations of physicians have been taught that Black people with high blood pressure should be treated with a narrower range of medication options than all other racial groups. This race-based approach to prescribing has no apparent patient benefit, according to a UC San Francisco study.

  2. May 29, 2018 · Data Synthesis: Numerous monotherapy trials indicate that black patients may have a reduced blood pressure (BP) response with ACE inhibitors or ARBs compared with white patients. Conversely, additional studies propose that race may not be the primary predictor of BP response.

    • Allison Helmer, Nicole Slater, Sean Smithgall
    • 2018
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  4. Abstract. Since the first International Society on Hypertension in Blacks consensus statement on the “Management of High Blood Pressure in African American” in 2003, data from additional clinical trials have become available.

    • John M. Flack, Domenic A. Sica, George Bakris, Angela L. Brown, Keith C. Ferdinand, Richard H. Grimm...
    • 2010
  5. Jan 12, 2022 · The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack (ALLHAT) 7 clinical trial showed that Black hypertensives had a lesser systolic blood pressure response to the ACE inhibitor lisinopril than to chlorthalidone by ≈4 to 5 mm Hg over follow-up; the average systolic blood pressure response to lisinopril in Black ...

  6. An initial combination of lisinopril and atenolol is simply not an appropriate regimen in any uncomplicated HTN patient, particularly a black patient. African American Study of Kidney and Hypertension (AASK)

    • Stephen K Williams, Joseph Ravenell, Sara Seyedali, Sam Nayef, Gbenga Ogedegbe
    • 10.1016/j.pcad.2016.09.004
    • 2016
    • Nov-Dec 2016
  7. Jun 14, 2021 · Article, see p 2355. Black patients have the highest age-adjusted prevalence of hypertension (57.6% of men and 53.2% of women), and their blood pressure (BP) is less well controlled despite being more likely to be diagnosed, treated, and treated more intensively. 1 In 2017, the death rate from hypertension (per 100 000 population) was 23 in White men, 54.1 in Black men, 18.6 in White women ...

  8. When evaluated by race, black patients had a higher risk of stroke with lisinopril vs chlorthalidone (RR 1.40; 95% CI, 1.17-1.68) and for combined cardiovascular disease (RR: 1.19; 95% CI, 1.09-1.30).

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