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  1. Mar 17, 2021 · Jake Haendel suffered for months from "locked-in syndrome," a rare phenomenon in which a patient is unable to move or communicate but remains fully conscious. But unlike most locked-in patients, Haendel recovered—and now he's sharing what the experience was like, Josh Wilbur writes for The Guardian .

  2. Jul 25, 2021 · Sunday Morning. Surviving locked-in syndrome: How one man confounded expectations of death. July 25, 2021 / 9:10 AM EDT / CBS News. When 28-year old Jacob Haendel was rushed to a...

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  4. Feb 17, 2005 · The locked-in syndrome is caused by an insult to the ventral pons, most commonly an infarct, haemorrhage, or trauma. The characteristics of the syndrome are quadriplegia and anarthria with preservation of consciousness. Patients retain vertical eye movement, facilitating non-verbal communication.

    • Eimear Smith, Mark Delargy
    • 2005
  5. Locked-in syndrome is due to a ventral pons lesion, which deafferentiates the patient for most motor function (absent horizontal eye movements, no grimacing, no swallowing, no head movements, and no limb movements). Patients with locked-in syndrome have their eyes open, blink, and may have spontaneous vertical eye movements.

    • Sara Hocker, Eelco F. M. Wijdicks
    • 2015
  6. Jul 7, 2005 · This is the story of Nick, who has lived with locked-in syndrome since 2000. His narrative is interspersed with information on his condition and a commentary on the clinical and ethical issues that arise in locked-in syndrome.

    • Nick Chisholm, Grant Gillett
    • 10.1136/bmj.331.7508.94
    • 2005
    • BMJ. 2005 Jul 9; 331(7508): 94-97.
  7. Jul 29, 2021 · Locked-in syndrome (LIS) is a neurological disorder in which there is damage to the ventral pons and caudal midbrain. An ischemic cause, such as basilar artery occlusion, can often lead to LIS. LIS has three subtypes: classical, partial, and total.

  8. Jul 24, 2023 · Locked-in syndrome is caused by any lesion affecting the ventral pons, and midbrain; this includes vascular lesions, masses, infections, traumas, and demyelinating disorders. Vascular. The most common cause is a vascular complication in the form of a hemorrhagic or ischemic stroke.

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