Search results
Dec 8, 2022 · Stiff-person syndrome is an autoimmune disorder of the nervous system, often resulting in progressive, severe muscle stiffness and spasms of the lower extremities and back. It also can affect other body regions.
Apr 14, 2019 · Diagnosed with stiff-person syndrome — an extremely rare autoimmune neurologic condition — Tara Zier looked to Mayo Clinic for help. There she found valuable guidance and gained a new outlook on how to manage her condition.
Jun 10, 2024 · Stiff person syndrome is a rare, chronic condition that causes muscle stiffness and painful muscle spasms. The severity of symptoms varies from person to person. There’s no cure for stiff person syndrome, but treatment can help manage symptoms and slow the progression of the condition.
Dec 17, 2023 · If not treated appropriately, stiff-person syndrome can have an associated mortality if the whole body “locks up,” because it can potentially disrupt a person’s breathing. Fortunately, James was in the right place for the right treatment.
Feb 2, 2023 · From symptom onset to death, the course of SPS can range from 6-28 years. Although the treatment for SPS is available, it does not cure the syndrome. Many patients have a slow course of the disorder that is mostly without symptoms, punctuated by occasional episodes of stiffness.
Stiff person syndrome is a rare autoimmune neurological disorder that most commonly causes muscle stiffness and painful spasms that come and go and can worsen over time. However, some people experience other symptoms such as an unsteady gait, double vision or slurred speech.
- www.ncbi.nlm.nih.gov
- › …
- › Cureus
- › v.12(12); 2020 Dec
Dec 9, 2020 · Stiff-person syndrome (SPS) is a rare and disabling central nervous system disorder with no satisfactory treatment. Muscle rigidity, sporadic muscle spasms, and chronic muscle pain characterize SPS. SPS is strongly correlated with autoimmune diseases, and it is usual to find high titers of antibodies against acid decarboxylase (GAD65).
Jun 18, 2024 · Stiff-person syndrome (SPS) is a rare, progressive neurological disorder. Symptoms may include stiff muscles in the trunk (torso), arms, and legs; and greater sensitivity to noise, touch, and emotional distress, which can set off muscle spasms.
Drs Jennifer A. Tracy and Andrew McKeon of Mayo Clinic in Rochester, Minnesota, answer questions about Stiff Person Syndrome, including: What are the most important symptoms and lab tests to strongly suggest a diagnosis of Stiff Person Syndrome? What is the meaning of the GAD65 antibody? Is a positive GAD65 antibody always abnormal?
Jul 10, 2023 · Objectives: Review the etiology of stiff person syndrome (SPS). Describe the clinical presentation and diagnostic criteria of stiff person syndrome (SPS). Summarize the management options for stiff person syndrome (SPS).
