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The mesolimbic pathway, sometimes referred to as the reward pathway, is a dopaminergic pathway in the brain. [1] The pathway connects the ventral tegmental area in the midbrain to the ventral striatum of the basal ganglia in the forebrain .
The reward system (the mesocorticolimbic circuit) is a group of neural structures responsible for incentive salience (i.e., "wanting"; desire or craving for a reward and motivation), associative learning (primarily positive reinforcement and classical conditioning ), and positively-valenced emotions, particularly ones involving pleasure as a cor...
The mesolimbic pathway is a neural pathway that transports dopamine from the ventral tegmental area (VTA) to the nucleus accumbens, amygdala, and hippocampus. It is associated with reward, desire, and cognitive sensations, and has been implicated in conditions like addiction and depression.
The mesolimbic pathway consists of dopamine neuron somata in the ventral tegmental area and projects to the ventral striatum, also known as the nucleus accumbens, for the control of reward processing.
- Changliang Liu, Pascal S Kaeser
- 10.1016/j.conb.2019.01.001
- 2019
- 2019/08
The dopaminergic pathway mostly involved in reward is the so-called mesolimbic system, which is formed by projections of midbrain dopamine neurons of the ventral tegmental area (VTA) to the striatum, prefrontal cortex, amygdala, hippocampus, and many other structures of the limbic system.
- 10.1007/978-3-030-81147-1_4
- 2021
The mesolimbic pathway is a neural pathway in the brain that is primarily involved in reward behavior, as well as motivation, learning, and memory. From: Geophagia [2019], Amantadine and memantine: a comprehensive review for acquired brain injury [2020]
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Mar 26, 2021 · In the mammalian central nervous system, three large neural circuits are controlled by SN and VTA mDAergic neurons: the nigrostriatal, the mesolimbic, and the mesocortical pathways (Figure 1).