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  1. Aug 1, 2021 · Views. PDF. Share. Tools. This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted.

  2. Dec 1, 2018 · Our purpose in this clinical report is to provide a summary of the current epidemiology of neonatal sepsis among infants born at ≥35 0/7 weeks’ gestation and a framework for the development of evidence-based approaches to sepsis risk assessment among these infants.

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
  3. Dec 1, 2018 · Our purpose for this clinical report is to provide a summary of the current epidemiology of preterm neonatal sepsis and provide guidance for the development of evidence-based approaches to sepsis risk assessment among preterm newborn infants.

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
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  5. Dec 12, 2023 · Sepsis and septic shock are major causes of morbidity, mortality, and health care costs for children worldwide, including >3 million deaths annually and, among survivors, risk for new or worsening functional impairments, including reduced quality of life, new respiratory, nutritional, or technological assistance, and recurrent severe infections. Advances in understanding sepsis pathophysiology ...

  6. Open the PDF Link PDF for Management of Neonates Born at ≥34 6/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis in another window Strategies for Prevention of Health Care–Associated Infections in the NICU

  7. Sepsis is an overwhelming and life-threatening response to an infection that can cause dysfunction of multiple organ systems. In pediatrics, diagnosing sepsis is especially challenging as children can compensate for severe illness for prolonged periods.

  8. a single CRP value for proven sepsis was 64% (95% CI 53 to. 59) with a positive predictive value of only 14% (95% CI 11 to. 17).45 However, if serial CRP values remain normal, there is a low likelihood of infection with a negative predictive value of nearly 100%46 The 2021 NICE guidelines recommend use of.

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