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Pediatrics. Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
Dec 1, 2018 · Pediatrics (2018) 142 (6): e20182894. The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last 2 decades, primarily because of the implementation of evidence-based intrapartum antimicrobial therapy. However, EOS remains a serious and potentially fatal illness.
- Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
- 2018
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Jan 22, 2021 · Our most recent results of neonatal sepsis incidence in the past decade (2009–2018) indicate an approximately four times higher number of global neonatal sepsis cases than the GBD estimates (3930 vs 937 cases per 100 000), likely due to different methodologies, such as varying case definitions, data collection methods and data inputs from ...
- Carolin Fleischmann, Felix Reichert, Alessandro Cassini, Rosa Horner, Thomas Harder, Robby Markwart,...
- 10.1136/archdischild-2020-320217
- 2021
- Arch Dis Child. 2021 Aug; 106(8): 745-752.
Sep 29, 2022 · Neonatal sepsis refers to an infection involving the bloodstream in newborn infants less than 28 days old. It remains a leading cause of morbidity and mortality among neonates, especially in middle and lower-income countries [1].
- Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
- 2022/09/29
Jan 22, 2021 · Sepsis is a dysregulated host response to infection leading to life- threatening organ dysfunction.1 Although neonates are highly vulnerable to sepsis, incidence estimates for this age group are lacking from many countries.2 Recently, the Global Burden of Disease (GBD) Study 2016/2017 estimated 1.3 (95% CI 0.8 to 2.3) million annual incident cas...
- 714KB
- Carolin Fleischmann, Felix Reichert, Alessandro Cassini, Rosa Horner, Thomas Harder, Robby Markwart,...
- 8
- 2021
Jan 22, 2021 · Random-effects estimator for neonatal sepsis incidence in the overall time frame was 2824 (95% CI 1892 to 4194) cases per 100 000 live births, of which an estimated 17.6% 9 (95% CI 10.3% to...
We estimate 48 children per 100 000 population develop sepsis, 22 children per 100 000 population develop severe sepsis, and 2202 neonates per 100 000 livebirths develop neonatal sepsis, with mortality of 11–19%. This would translate to an incidence of 3·0 million cases of neonatal sepsis and 1·2 million cases of paediatric sepsis annually.
