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SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin changes. These diseases share some clinical, radiologic, and pathologic characteristics. An entity initially known as chronic recurrent multifocal osteomyelitis was first described in 1972.
Jun 7, 2024 · The SAPHO syndrome was given its acronymic name based upon the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis in the patients described in early reports. It is a rare inflammatory disorder of bone, joints, and skin, which was first described as a syndrome in 1987 .
Mar 2, 2020 · SAPHO syndrome is a rare disorder with a wide range of possible symptoms. Some common symptoms include blisters, acne, and inflammation of the joints and bones.
SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones).
Dec 26, 2023 · Synovitis acne pustulosis hyperostosis osteitis (SAPHO) is a syndrome encompassing musculoskeletal and dermatological manifestations, for which there are currently no agreed standard treatment protocols.
Jul 23, 2020 · Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a constellation of dermatological and osteoarticular symptoms. The pathogenesis of SAPHO is unknown, but infectious, genetic, immunological and environmental factors may play a role.
SAPHO syndrome is suspected when a patient presents with a pustular skin disease in association with rheumatic pain. Magnetic resonance imaging (MRI scan) shows inflammation of the bone marrow or joints at characteristic sites such as the collar bone, breast bone, pelvis, heel, and lower jaw.
SAPHO syndrome, an acronym for synovitis, acne, pustu-lar lesions, hyperostosis, and osteitis, is a rare, complex, and chronic inflammatory rheumatic disease that often fol-lows a relapsing course [1–4]. First identified in the late. * Tuba Demirci Yildirim tubademirci87@gmail.com. İsmail Sari ismailsari35@gmail.com.
Oct 27, 2023 · SAPHO syndrome, an acronym for synovitis, acne, pustular lesions, hyperostosis, and osteitis, is a rare, complex, and chronic inflammatory rheumatic disease that often follows a relapsing course [1,2,3,4].
SAPHO syndrome encompasses a wide spectrum of anomalies characterized by variable combinations of osteoarticular and cutaneous manifestations of varying degrees of severity. The onset of bone and joint pain, stiffness and swelling is most often insidious.
