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  1. Jun 15, 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.

  2. Scleroderma makes your body produce too much collagen, a protein that you need for healthy skin and tissue. It’s an autoimmune condition, which means your immune system attacks your body instead of protecting it. Scleroderma can cause lots of symptoms and affect tissue throughout your body.

  3. Feb 8, 2023 · Systemic sclerosis (SS) is an autoimmune disorder that causes atypical growth of connective tissues. Connective tissue gives your tissues (organs and muscles) strength and shape. With SS, your...

  4. Scleroderma is an autoimmune, rheumatic, and chronic disease that affects the body by hardening connective tissue. (“Connective tissue” is widespread. It adds strength to organs and other parts of the body.) Connective tissue is made of many kinds of proteins. Among them is collagen of the skin.

  5. Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma.

  6. Feb 27, 2024 · Scleroderma is a long-lasting autoimmune disease that affects your skin, connective tissue, & internal organs. Learn about types, causes, risk factors, symptoms, diagnosis & treatment.

  7. Jun 15, 2024 · This group of rare diseases involves the hardening and tightening of the skin and connective tissues. Some forms can affect internal organs.

  8. en.wikipedia.org › wiki › SclerodermaScleroderma - Wikipedia

    Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2][ 6][ 8] The disease can be either localized to the skin or involve other organs, as well. [ 2] .

  9. Scleroderma is a rare rheumatic disease that affects connective tissue and the vascular system producing excessive collagen that causes fibrosis in the skin (localized) or in internal organs (systemic sclerosis).

  10. Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic ...

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