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Midbrain structure
- The ventral tegmental area (VTA) is a midbrain structure in the mesolimbic reward circuit consisting of predominantly dopaminergic neurons.
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The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.
Sep 14, 2023 · Central to this system are the Ventral Tegmental Area (VTA) and the Nucleus Accumbens (NAc). When a rewarding stimulus is perceived, dopamine is released from the VTA, acting on the NAc, leading to feelings of pleasure. Dysfunctions in this pathway can underlie addiction and other behavioral disorders.
May 20, 2022 · The ventral tegmental area (VTA) is well known for regulating reward consumption, learning, memory, and addiction behaviors through mediating dopamine (DA) release in downstream regions. Other than DA neurons, the VTA is known to be heterogeneous and contains other types of neurons, including glutamate neurons.
- Jing Cai, Qingchun Tong
- Front Neural Circuits. 2022; 16: 867053.
- 10.3389/fncir.2022.867053
- 2022
Apr 29, 2013 · VENTRAL TEGMENTAL AREA. a region inside the midbrain ventral onto the periaqueductal gray and the dorsal to the substantial nigra. It makes up a portion of the limbic system, carrying dopaminergic neurons to the mesolimbic and mesocortical system.
Apr 19, 2018 · ventral tegmental area. an area in the midbrain ventral to the periaqueductal gray and dorsal to the substantia nigra. It forms part of the limbic system, sending dopaminergic neurons to the mesocortical system and mesolimbic system.
Jan 5, 2017 · Ventral tegmental area (VTA) dopamine neurons (which we here define as those neurons that express the dopamine-producing enzyme tyrosine hydroxylase (TH) and release dopamine (...
Ventral tegmental area (VTA) contains cell bodies of dopaminergic neurons projecting to the nucleus accumbens, amygdala, hippocampus, and prefrontal cortex. Defined as the mesocorticolimbic dopamine system ( Albanese and Minciacchi, 1983 ), these neurons are critically implicated in brain mechanisms of reward, reinforcement, and emotional ...