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  1. May 20, 2022 · Abstract. The ventral tegmental area (VTA) is well known for regulating reward consumption, learning, memory, and addiction behaviors through mediating dopamine (DA) release in downstream regions. Other than DA neurons, the VTA is known to be heterogeneous and contains other types of neurons, including glutamate neurons.

  2. The ventral tegmental area ( VTA) ( tegmentum is Latin for covering ), also known as the ventral tegmental area of Tsai, [1] or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain. The VTA is the origin of the dopaminergic cell bodies of the mesocorticolimbic dopamine system and other ...

  3. Sep 14, 2023 · The brain's reward system is a network of structures responsible for pleasure, motivation, and reinforcement learning. Central to this system are the Ventral Tegmental Area (VTA) and the Nucleus Accumbens (NAc). When a rewarding stimulus is perceived, dopamine is released from the VTA, acting on the NAc, leading to feelings of pleasure. Dysfunctions in this pathway can underlie addiction and ...

  4. Jan 5, 2017 · Neurons in the ventral tegmental area (VTA) are highly heterogeneous and project to a range of different brain regions. Morales and Margolis summarize recent efforts to characterise VTA neurons ...

    • Marisela Morales, Elyssa B. Margolis
    • 2017
  5. The ventral tegmental area (VTA) is a brain region centrally involved in the development and expression of a variety of behaviors associated with drug use. Hypocretin (hcrt), also known as orexin, is a lateral hypothalamic neuropeptide that can be released into the VTA. An increasing number of studies show that hcrt in the VTA exerts modulatory ...

  6. Oct 17, 2023 · The ventral tegmentum is one of these areas. The ventral tegmentum is composed of a number of neurons that are located in the midbrain. They are found on the floor of the brain close to the midline brain. The ventral tegmentum plays a significant role in a number of functions, including those associated with reward.

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  8. The ventral tegmental area, or VTA, is in the midbrain, situated adjacent to the substantia nigra. Although it contains several different types of neurons, it is primarily characterized by its dopaminergic neurons, which project from the VTA throughout the brain. The VTA is considered an integral part of a network of structures, together known ...

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