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  1. May 20, 2022 · The ventral tegmental area (VTA) located in the midbrain controls diverse behavioral repertoire, including reward processing, aversion, stress modulation, drug addiction, learning, and memory ( Haber and Fudge, 1997; Ikemoto, 2007; Arias-Carrion et al., 2010; Polter and Kauer, 2014 ).

  2. Thus, the ventral tegmental area is reciprocally connected with a wide range of structures throughout the brain suggesting that it has a role in the control of function in the phylogenetically newer and highly developed neocortex, as well as that of the phylogenetically older limbic areas.

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  4. The ventral tegmental area, or VTA, is in the midbrain, situated adjacent to the substantia nigra. Although it contains several different types of neurons, it is primarily characterized by its dopaminergic neurons, which project from the VTA throughout the brain.

  5. Jan 5, 2017 · Ventral tegmental area (VTA) dopamine neurons (which we here define as those neurons that express the dopamine-producing enzyme tyrosine hydroxylase (TH) and release dopamine ( Box 1) are...

    • Marisela Morales, Elyssa B. Margolis
    • 2017
  6. Jul 8, 2021 · July 8, 2021. Table of Contents. Introduction. Location. Structure: Subdivisions: The function of VTA: Clinical Significance: Disorders of VTA: The Ventral Tegmental Area, also known as the VTA, is a small cluster of neurons in our midbrain right in the bottom center. Click for more information.

  7. Anatomy and Function of Ventral Tegmental Area Glutamate Neurons. The ventral tegmental area (VTA) is well known for regulating reward consumption, learning, memory, and addiction behaviors through mediating dopamine (DA) release in downstream regions.

  8. The dopaminergic pathway mostly involved in reward is the so-called mesolimbic system, which is formed by projections of midbrain dopamine neurons of the ventral tegmental area (VTA) to the striatum, prefrontal cortex, amygdala, hippocampus, and many other structures of the limbic system.

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