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In these settings, maternal anemia and delivery of low birth-weight infants (<2500 g or <5.5 pounds) are frequent complications of malaria. It is a particular problem for women in their first and second pregnancies, for younger women, and for women who are HIV-positive.
Mar 27, 2024 · Complications. IV artesunate is well tolerated. The only formal contraindication to IV artesunate treatment is known allergy to IV artemisinins. While rare, delayed post-artemisinin hemolytic anemia has been noted in published case reports following treatment of severe malaria with IV artesunate.
The commonest, most important complications of P. falciparum infection in children are cerebral malaria, severe anaemia, respiratory distress (acidosis) and hypoglycaemia. The differences between severe malaria in adults and in children are shown in Table 1.
Mar 27, 2024 · Overview. Healthcare providers can report serious side effects to antimalarials to FDA via MedWatch, FDA's Safety Information and Adverse Event Reporting Program, or by phone at (800) FDA-1088 (800-332-1088) or fax at (800) FDA-0178 (800-332-0178).
Of primary importance in the treatment of malaria is the provision of prompt, effective therapy and concurrent supportive care to manage life-threatening complications of the disease. Supportive measures, such as fluid management, oxygen, ventilatory support, cardiac monitoring, and pulse oximetry, should be instituted as needed.
- 10.1007/978-3-319-43341-7_57
- 2016 Jul
Aug 8, 2023 · Patients taking both drugs should be monitored closely for increased bleeding episodes. Artemether-lumefantrine's most common side effects include headache, fever, dizziness, fatigue, nausea and vomiting, and anorexia. Of note, for this medication, muscular effects are common and usually manifest as weakness and/or myalgia.
Mar 26, 2024 · Management of patients with severe malaria presents a broad array of clinical challenges given the complex pathophysiology of an infection that involves multiple organ systems. These challenges are increased in endemic areas where access to diagnostic and therapeutic tools may be limited.
