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  2. Pfizer-BioNTech COVID-19 Vaccine, Bivalentinclude the following ingredients: mRNAandlipids (((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2 [(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 1,2-Distearoyl-sn-glycero-3-phosphocholine, and cholesterol). Pfizer-BioNTech COVID-19 Vaccine for individuals 12 years of age ...

    • Overview
    • Common side effects
    • Allergic reactions and anaphylaxis
    • Pregnancy and fertility concerns
    • Heart health side effects
    • Should I receive the vaccine?

    The Pfizer-BioNTech COVID-19 vaccine may sometimes cause no side effects or mild-to-moderate side effects, which can be fairly common post-vaccination. This Snapshot feature further addresses concerns around allergic reactions and false claims regarding risks to pregnancy and fertility.

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    All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub for the most recent information on COVID-19.

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    Sex and gender exist on spectrums. This article will use the terms “male” and “female” to refer to a person’s sex assigned at birth.

    The Pfizer-BioNTech COVID-19 vaccine, named BNT162b2, and known as Comirnaty in the European Union, is a two-dose mRNA vaccine developed by two pharmaceutical industry companies: Pfizer in the United States and BioNTech in Germany.

    According to the FDA’s vaccine fact sheet, typical side effects of the Pfizer-BioNTech vaccine include:

    •tiredness

    •headache

    •fever

    •chills

    •muscle or joint pain

    Although rare, individuals may experience mild-to-severe allergic reactions to ingredients in the vaccine. Symptoms of severe reactions, or anaphylaxis, are listed in the vaccine fact sheet as:

    •difficulty breathing

    •swelling of face and throat

    •rapid heartbeat

    •rash

    •dizziness

    Concerns regarding the vaccine’s effects on fertility emerged when an internet source stated that the genetic information for the spike protein is similar to that of syncytin-1, a protein found in the placenta of mammals.

    The source — since removed from the web — claimed that the antibodies produced by the body in response to the vaccine, which targets the SARS-CoV-2 virus’ spike protein, could also target syncytin-1 and cause infertility.

    Scientists have demonstrated this claim to be inaccurate. Firstly, immunologists have shown no significant similarity between the genetic information of these two proteins, while blood plasma from COVID-19 patients does not react with syncytin-1.

    Secondly, if this claim were true, it would mean that natural SARS-CoV-2 infection would likely cause a higher rate of miscarriage. This has not been seen in studies examining the effects of COVID-19 — female participants with the disease did not display a higher risk of early pregnancy loss.

    Additionally, the vaccine’s clinical trials included 11 female participants in the vaccinated group who became pregnant during the trial, compared to a similar number of 12 female participants in the control group.

    While there is not yet long-term evidence regarding this claim, animal studies have also not reflected any evidence of fertility loss due to the vaccine.

    On June 25, 2021, the FDA added revisions to both the patient and healthcare provider fact sheets for the Pfizer-BioNTech COVID-19 vaccine, addressing the potential, if very rare, risks of myocarditis, or inflammation of the heart muscle, and pericarditis, which is inflammation of the lining outside the heart.

    In the patient fact sheet, the FDA notes that, for people who experienced myocarditis or pericarditis after their vaccine, “symptoms began within a few days following receipt of the second dose.” However, it also adds that “[t]he chance of having this occur is very low.”

    The FDA advises people to seek medical attention immediately should they experience chest pain, shortness of breath, or “feelings of having a fast-beating, fluttering, or pounding heart” after receiving the Pfizer-BioNTech vaccine.

    The CDC further notes that these side effects are most likely to occur in adolescents and young adults, and that most of those who receive immediate care respond well to treatment and their condition quickly improves.

    Regulatory agencies are keeping a close eye on the safety of COVID-19 vaccines. Up to this point, there have not been any risk indications that require a pause in distribution for the Pfizer-BioNTech vaccine.

    Additionally, health experts note that while some people may experience minor or moderate side effects after vaccination, these typically go away after a few days.

    The CDC recommends that anyone who does not have known allergies to the vaccine ingredients, or relevant contraindications, receive the vaccine to prevent severe illness or death and reduce the chances of contracting COVID-19.

    For live updates on the latest developments regarding the novel coronavirus and COVID-19, click here.

  3. Apr 28, 2023 · Pfizer-BioNTech COVID-19 Vaccine, Bivalent contains the following ingredients: messenger ribonucleic acid (mRNA), lipids (((4-hydroxybutyl)azanediyl)bis(hexane-6,1-

  4. Oct 24, 2022 · After the FDA approved Pfizer's COVID-19 vaccine in the US, they made public the ingredient list of the vaccine. Here's what's in it.

  5. Dec 9, 2020 · monobasic potassium phosphate. sodium chloride. basic sodium phosphate dihydrate. Other. sucrose. Reading the ingredient list is like looking at the side of a cereal box, except...

    • Antonio Regalado
  6. Sep 15, 2023 · Side Effects. Risk of Myocarditis and Pericarditis. Funding. Pfizer’s BNT162b2 mRNA Covid-19 vaccine was the first vaccine against the novel coronavirus (COVID-19) approved for distribution in the United States. The approval came as an emergency use authorization on December 11, 2020, after clinical trials showed the vaccine was 95% effective ...

  7. People should talk to their healthcare provider before getting an mRNA COVID-19 vaccine if they: Have had an immediate allergic reaction to a previous dose of an mRNA COVID-19 vaccine that was not severe. Have had an allergic reaction to an ingredient in the mRNA COVID-19 vaccine that was not severe.

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  2. 65 And Older & Got A 2023-24 COVID-19 Shot? You May Be Eligible For An Additional Dose. Use The Vaccine Finder To Find COVID-19 Vax Locations Near You & Help Stay Protected.