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  1. Jan 6, 2018 · Autism spectrum disorder has no single known cause. Given the complexity of the disorder, and the fact that symptoms and severity vary, there are probably many causes. Both genetics and environment may play a role.

  2. Aug 20, 2019 · Autism is estimated to be 40–80% heritable. However, both genetic and non-genetic factors modulate the penetrance of risk genes, resulting in a highly heterogeneous disease phenotype for similar pathogenic variants. Examples of genetic modulators include CNV, epigenetics, and double-hit mutations. Examples of non-genetic modifiers include ...

    • Lauren Rylaarsdam, Alicia Guemez-Gamboa
    • 10.3389/fncel.2019.00385
    • 2019
    • Front Cell Neurosci. 2019; 13: 385.
  3. Aug 20, 2021 · The cause of ASD is unknown, but several genetic and non-genetic risk factors have been characterized that, alone or in combination, are implicated in the development of ASD.

    • Ann Katrin Sauer, Janelle E. Stanton, Sakshi Hans, Andreas M. Grabrucker
    • 2021/08/20
    • 2021
  4. Scientists don't know exactly what causes autism spectrum disorder (ASD). Autism was first described in the 1940s, but very little was known about it until the last few decades. Even today, there is a great deal that we don't know about autism.

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  6. Mar 31, 2021 · What Causes Autism Spectrum Disorder? Genetics. Environment. Biology. Risk factors. About vaccines. Diagnosis. Recap. Genetic factors play a big role in causing autism spectrum...

  7. Jul 4, 2011 · A new Stanford University School of Medicine study of twins suggests that non-genetic factors play an unexpectedly large role in determining autism risk, turning upside down recent assumptions about the cause of this common, disabling developmental disorder.

  8. Autism spectrum disorder (ASD) is a developmental disability caused by differences in the brain. Some people with ASD have a known difference, such as a genetic condition. Other causes are not yet known. Scientists believe there are multiple causes of ASD that act together to change the most common ways people develop.

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