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  1. www.ncbi.nlm.nih.gov › pmc › articlesUpdates in Late-Onset Sepsis: Risk Assessment, Therapy and...

    Nov 11, 2022 · Abstract. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality within the neonatal intensive care unit (NICU) and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  2. publications.aap.org › neoreviews › articleUpdates in Late-Onset Sepsis: Risk Assessment, Therapy, and ...

    Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preterm infants—born at ever-decreasing gestational ages—are at particularly high risk for life ...

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  4. www.ncbi.nlm.nih.gov › pmc › articlesRisk Factors and Prevention of Late Onset Sepsis in Premature ...

    Abstract. Late-onset sepsis in premature infants is a major cause of morbidity, mortality, and increased medical costs. Risk factors include low birth weight, low gestational age, previous antimicrobial exposure, poor hand hygiene, and central venous catheters. Methods studied to prevent late-onset sepsis include early feedings, immune globulin ...

    • L. Corbin Downey, P. Brian Smith, Daniel K. Benjamin
    • 10.1016/j.earlhumdev.2010.01.012
    • 2010
    • 2010/07

  5. www.healthcare.uiowa.edu › marcom › uichildrensLate Onset Sepsis Prophylaxis and Treatment 2022

    Vancomycin 15 mg/kg is infused through the central line that will be removed over 90 minutes. The peak serum Vancomycin concentration is reached approximately 30 minutes after the end of the infusion, so the central line is removed after the 30 minute post-Vancomycin flush is completed. II. Evaluation and Treatment.

  6. renaissance.stonybrookmedicine.edu › sites › defaultLate-onset Sepsis: Epidemiology, Evaluation, and Outcome ...

    late-onset sepsis contributes to improved neonatal prognosis, but the outcome remains far from satisfactory. Objectives After completing this article, readers should be able to: 1. Understand the difficulties of diagnosing late-onset sepsis clinically and via laboratory tests and optimal use of available markers. 2. Describe new diagnostic ...

  7. www.nature.com › articles › s41372/019/0577-5Standardizing the approach to late onset sepsis in neonates ...

    Jan 6, 2020 · Late onset sepsis (LOS; i.e., sepsis onset >72 h after birth) remains a leading cause of neonatal mortality [].It often presents with nonspecific signs of illness (e.g., temperature instability ...

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