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In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
Feb 11, 2018 · The median lethal dose, or LD50, is a term used in toxicology as a measurement of a lethal dose of a substance (e.g., pathogen, medication, toxic substance, etc.). Specifically, the LD50 represents the dose at which a substance is lethal for 50% of tested subjects.
May 10, 2024 · What does LD 50 mean? Back to top. LD stands for "Lethal Dose". LD 50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material.
Jun 17, 2016 · Dose descriptors are determined in the toxicological studies on the hazards of the substance and are usually expressed as LC50, LD50, NOAEL, NOAEC, T25, BMD, EC50, NOEC, DT50, etc. They are used for GHS hazard classification and risk assessment.
Jun 20, 2014 · Definition: The median lethal dose of a substance, or the amount required to kill 50% of a given test population. LD50 is a measurement used in toxicology studies to determine the potential impact of toxic substances on different types of organisms.
The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.
Dec 21, 2020 · Acute lethality provides one simple, generalized indicator of the toxicity of a chemical product. The acute lethality hazard is typically determined using the LD 50 which is defined as the median dose predicted to kill 50% of a given test population.
