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  1. www.nature.com › articles › s41386/021/01209-wThe addiction risk factor: A unitary genetic vulnerability ...

    Nov 8, 2021 · Third, we examine whether The Addiction-Risk-Factor is associated with the 3 factors representing genetic liability to non-substance psychopathology (i.e., psychotic, compulsive, and ...

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  2. www.nature.com › articles › s41386/020/00950-yAddiction as a brain disease revised: why it still matters ...

    Feb 22, 2021 · The view that substance addiction is a brain disease, although widely accepted in the neuroscience community, has become subject to acerbic criticism in recent years. These criticisms state that ...

    • Markus Heilig, James MacKillop, James MacKillop, Diana Martinez, Jürgen Rehm, Lorenzo Leggio, Louk J...
    • 2021

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  4. www.ncbi.nlm.nih.gov › pmc › articlesConflicting theories on addiction aetiology and the strengths ...

    Sep 6, 2023 · A summary of leading theories on addiction aetiology; the three-stage brain disease model, concepts in genetic modelling and behavioural theories of addiction, and their interrelationships. Contrasting opinions on the causative factor of addiction between neurobiology, behaviour and genetics is commonplace in the literature across fields.

    • Megan R. Greener, Sarah J. Storr
    • Front Mol Neurosci. 2023; 16: 1166852.
    • 10.3389/fnmol.2023.1166852
    • 2023

  5. ajp.psychiatryonline.org › doi › fullNeuroscience of Addiction: Relevance to Prevention and ...

    Apr 25, 2018 · The delineation of the neurocircuitry disrupted in addiction, which includes circuits that mediate reward and motivation, executive control, and emotional processing, has given us an understanding of the aberrant behaviors displayed by addicted individuals and has provided new targets for treatment.

    • Nora D. Volkow, Maureen Boyle
    • 2018

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  7. www.psychologytoday.com › us › blogUnderstanding Individual Vulnerability to Addiction ...

    Jun 5, 2022 · Addiction is a complex disorder influenced by genetics, reward circuitry, early life experiences, and social situations. The moral model erroneously attributes the cause of addiction to one's ...

  8. www.nature.com › articles › s44159/024/00307-yMechanisms linking social media use to adolescent mental ...

    May 7, 2024 · Mechanisms and predisposing factors can interact and combine, amplifying mental health vulnerability. Mental health can be considered a dynamic system in which gradual changes to external ...

  9. www.mdpi.com › 2813/1851/3-1 › 3Neurobiological Theories of Addiction: A Comprehensive Review

    Jan 23, 2024 · However, the opponent-process theory falls short in explaining individual variability in addiction vulnerability, that is, why not all individuals with repeated exposure to a drug develop addiction. Moreover, it does not make any reference to the involved brain mechanisms.