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What causes a morbilliform drug eruption?
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The eruption may resemble exanthems caused by viral and bacterial infections. A morbilliform skin rash in an adult is usually due to a drug. In a child, it is more likely to be viral in origin. Morbilliform drug eruption is also called maculopapular drug eruption, exanthematous drug eruption and maculopapular exanthem.
May 1, 2024 · 6 min read. What Is a Morbilliform Rash? A morbilliform rash is any rash that looks a lot like measles. The word “morbilliform” means measles-like. Sometimes dermatologists call them morbilliform...
Mar 13, 2019 · The eruption usually begins on the trunk and upper extremities and progresses caudally. It is usually symmetric. Confluence and severity is worst in dependent areas, such as the back in hospitalized patients (Figure 1). The face may be involved, but mucous membranes are typically spared.
Jan 12, 2023 · Rosamaria Corona, MD, DSc. Literature review current through: Mar 2024. This topic last updated: Jan 12, 2023. INTRODUCTION. Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ].
Mar 8, 2021 · Exanthematous (morbilliform) drug eruptions are the most common type of adverse drug reaction. Thought to be delayed-type, T cell-mediated immune reaction. Characterized by erythematous macules and papules coalescing into patches and plaques without secondary change that predominantly involve the trunk and proximal extremities.
There are many types of drug eruption, which range from a clinically mild and unnoticed rash to a severe cutaneous adverse reaction (SCAR) that may be life-threatening. The most common drug eruptions are: Morbilliform or exanthematous drug eruption. Urticaria and/or angioedema (which rarely leads to anaphylaxis ). SCARs are rare:
It is seen in children and adults most often as a morbilliform cutaneous eruption with fever, lymphadenopathy, hematologic abnormalities, and multiorgan manifestations. Historically, it was most frequently linked with phenytoin and known as phenytoin hypersensitivity syndrome.
