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  1. This body of experimental domestication research has provided crucial information about the nature of the DS because it overcomes the difficulty of disentangling the initial genetic changes in the domestication of many breeds, which took place centuries or millennia ago, from the many later (and more specific) genetic changes resulting from ...

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      Neural crest cell genes: Dosage effects and genetic...

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      MRC Brain Development Programme,Department of Developmental...

  2. Jul 19, 2021 · The term “domestication syndrome” has been applied for about four decades to a set of correlated changes in “domesticated” plants, namely crop plants. We use it to refer to a suite of changes in mammals and birds—but which probably occurs in vertebrates including fishes—that distinguish many different domesticated animals from their ...

    • Adam S Wilkins, Richard Wrangham, W Tecumseh Fitch
    • 10.1093/genetics/iyab098
    • 2021
    • Genetics. 2021 Sep; 219(1): iyab098.
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  4. Jul 1, 2014 · Most explanations focus on particular traits, while neglecting others, or on the possible selective factors involved in domestication rather than the underlying developmental and genetic causes of these traits. Here, we propose that the domestication syndrome results predominantly from mild neural crest cell deficits during embryonic development.

    • Adam S. Wilkins, Adam S. Wilkins, Richard W. Wrangham, Richard W. Wrangham, W. Tecumseh Fitch
    • 2014
  5. Feb 11, 2022 · Abstract. Neural crest cell genes control the migration of neural crest cells to multiple parts of developing vertebrate embryos. A recent hypothesis posits that the “domestication syndrome” characteristic of domesticated animals is driven by selection for tameness acting on neural crest cell genes, particularly those affecting cell migration.

    • Andrew O. Rubio, Kyle Summers
    • PLoS One. 2022; 17(2): e0263830.
    • 10.1371/journal.pone.0263830
    • 2022
  6. The origin of Darwin's "domestication syndrome" has remained a conundrum for more than 140 years. Most explanations focus on particular traits, while neglecting others, or on the possible selective factors involved in domestication rather than the underlying developmental and genetic causes of these traits.

    • Adam S. Wilkins, Adam S. Wilkins, Richard W. Wrangham, Richard W. Wrangham, W. Tecumseh Fitch
    • 2014
  7. drome. We then explore the genetic implications of the idea, including a brief look at some intriguing developmental, evolutionary, and genetic questions that the idea raises. We end with some predictions and a discussion of experi-ments and analyses to test the hypothesis. Previous Thinking About the Genetic Basis of the Domestication Syndrome

  8. Domestication syndrome refers to two sets of phenotypic traits that are common to either domesticated plants [1] [2] or domesticated animals. [3] Domesticated animals tend to be smaller and less aggressive than their wild counterparts, they may also have floppy ears, variations to coat color, a smaller brain, and a shorter muzzle.

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