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Supportive Care: Sufficient fluid and calorie intake, and additional oxygen supplementation should be used in the treatment of children infected with COVID-19. The aim is to prevent ARDS, organ failure, and secondary nosocomial infections. If bacterial infection is suspected, broad-spectrum antibiotics may be used.22.
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- Table 3a. Therapeutic Management of Nonhospitalized Children With COVID-19
- Table 3c. Therapeutic Management of Hospitalized Children With COVID-19
- Table 3d. Therapeutic Management of Hospitalized Pediatric Patients With MIS-C
- References
Symptomatic, Regardless of Risk Factors
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Aged 12–17 Years
••Provide supportive care (AIII).
Aged <12 Years
••Provide supportive care (AIII).
Hospitalized for COVID-19
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For children aged ≥12 years admitted for COVID-19, use prophylactic anticoagulation unless contraindicated (BIII).a
•Weighing the risk factors for thrombosis and bleeding, some Panel members would use prophylactic anticoagulation for children aged <12 years who are hospitalized for COVID-19.
Does Not Require Supplemental Oxygen
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MIS-C
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Initial treatment for MIS-C includes both immunomodulatory and antithrombotic therapy.
Initial Immunomodulatory Therapy
•IVIG 2 g/kg IBW (up to a maximum total dose of 100 g) IV plus low to moderate dose methylprednisolone (1–2 mg/kg/day) IVa or another glucocorticoid at an equivalent dosea (AIIb).
•Glucocorticoid monotherapy, only if IVIG is unavailable or contraindicated (BIIa).
Centers for Disease Control and Prevention. COVID-19 weekly cases and deaths per 100,000 population by age, race/ethnicity, and sex. 2023. Available at: https://covid.cdc.gov/covid-data-tracker/#demographicsovertime. Accessed June 23, 2023.
Centers for Disease Control and Prevention. Provisional COVID-19 deaths: focus on ages 0–18 years. 2023. Available at: https://data.cdc.gov/NCHS/Provisional-COVID-19-Deaths-Focus-on-Ages-0-18-Yea/nr4s-juj3. Accessed June 23, 2023.
Centers for Disease Control and Prevention. Demographic trends of COVID-19 cases and deaths in the US reported to CDC. 2023. Available at: https://covid.cdc.gov/covid-data-tracker/#demographics. Accessed June 23, 2023.
Centers for Disease Control and Prevention. COVID-NET laboratory-confirmed COVID-19 hospitalizations. 2023. Available at: https://covid.cdc.gov/covid-data-tracker/#covidnet-hospitalization-network. Accessed June 23, 2023.
Key Considerations. SARS-CoV-2 infection is generally milder in children than in adults, and a substantial proportion of children with the infection are asymptomatic. Most nonhospitalized children with COVID-19 will not require any specific therapy. Children with ≥1 of the following comorbidities are at increased risk of severe COVID-19 ...
Sep 30, 2021 · A total of 21% children received at least one medication specifically used for COVID-19. While antivirals were used in 15.3% of children, remedesivir was the most commonly used antiviral drug in 6.2% of included children without many reports of serious adverse effects.
Mar 7, 2023 · The virus that causes COVID-19 is designated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In children, COVID-19 is usually mild. However, in rare cases, children can be severely affected, and clinical manifestations may differ from adults.
Mar 29, 2021 · In this mini review, we summarize some of the mechanisms and findings that distinguish between adult and pediatric COVID-19 and respiratory involvement, taking into account some issues related to the physiopathology, diagnosis, clinical and paraclinical presentation, severity, treatment, and control of the disease.
- Jenny Libeth Jurado Hernández, Iván Francisco Álvarez Orozco
- 10.3389/fped.2021.622240
- 2021
- Front Pediatr. 2021; 9: 622240.
Apr 12, 2024 · The clinical spectrum of COVID-19 ranges from asymptomatic infection to mild respiratory tract symptoms to severe pneumonia with acute respiratory distress syndrome and multiorgan dysfunction. Understanding of COVID-19 is evolving. The World Health Organization, the United States Centers for Disease Control and Prevention, the American Academy ...
