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Jul 4, 2023 · Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria. This activity will discuss the indications, mechanism of action, and contraindications of using streptomycin ...
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
In veterinary medicine, streptomycin is the first-line antibiotic for use against gram negative bacteria in large animals ( horses, cattle, sheep, etc.). It is commonly combined with procaine penicillin for intramuscular injection. [medical citation needed] Tularemia infections have been treated mostly with streptomycin.
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Aug 18, 2020 · For example, copper resistant P. aeruginosa was isolated from a French water system and tap aeration grids, and hydrogen peroxide and silver nitrate resistant Legionella spp. were isolated from a hospital’s water supply [57,77]. Future work is needed to inform and improve HAI guidelines regarding the use of water and prevent the spread of AMR ...
- Claire Hayward, Kirstin E. Ross, Melissa H. Brown, Harriet Whiley
- 10.3390/pathogens9080667
- 2020
- Pathogens. 2020 Aug; 9(8): 667.
streptomycin, antibiotic synthesized by the soil organism Streptomyces griseus. Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins. It was the first antimicrobial agent developed ...
- The Editors of Encyclopaedia Britannica
Common side effects of streptomycin may include: nausea, vomiting, and dizziness; diarrhea; numbness, tingling, or swelling in your face; fever; rash; or. vaginal itching or discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
1. Streptomycin is active against Gram (-) negative bacteria. It is used in the treatment of tuberculosis caused by Mycobacterium tuberculi. 2. It is also used therapeutically in the treatment of infectious diseases caused by Gram (-) negative bacteria, specially those organisms which are resistant to penicillin. 3.
Streptomycin production is a process used for producing the antibiotic streptomycin from a strain of actinomycetes. The large-scale manufacture of streptomycin utilizes Streptococcus griseus and makes advantage of the carbon, nitrogen, mineral sources, etc. present in the fermentation medium. It has a strong inhibitory effect on gram-positive ...
