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    • Image courtesy of thelancet.com

      thelancet.com

      • Systemic illness caused by microbial invasion of normally sterile parts of the body is referred to as “sepsis.” This is a term that specifically serves to differentiate an illness of microbial origin from an identical clinical syndrome that can arise in several non-microbial conditions, of which pancreatitis is the archetype.
      www.bmj.com › content › 335/7625/879
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  2. Mar 4, 2021 · In 2017, the international Surviving Sepsis Campaign (iSSC) published revised guidelines for the diagnosis and treatment of sepsis and septic shock after publication of the Sepsis-3 definition in 2016, a renewed definition of sepsis as life-threatening organ dysfunction caused by a dysregulated host response to an infection [3, 4].

  3. May 21, 2023 · Bacterial sepsis is a life-threatening condition that arises when the body's response to an infection injures its tissues and organs. Sepsis is caused by conditions that threaten the functional integrity of the host, such as microbial invasion.

  4. Oct 10, 2007 · What is sepsis? Systemic illness caused by microbial invasion of normally sterile parts of the body is referred to as “sepsis.” This is a term that specifically serves to differentiate an illness of microbial origin from an identical clinical syndrome that can arise in several non-microbial conditions, of which pancreatitis is the archetype.

    • Andrew Lever, Iain Mackenzie
    • 10.1136/bmj.39346.495880.AE
    • 2007
    • BMJ. 2007 Oct 27; 335(7625): 879-883.
  5. Bacteremia, sepsis, severe sepsis, and septic shock are related: Bacteremia: Bacteria are present in the bloodstream. Bacteremia can result from a serious infection or from something as harmless as vigorous toothbrushing. Most often, only a small number of bacteria are present, and they are removed by the body on its own.

  6. Feb 3, 2020 · Sepsis is a clinical syndrome that has physiologic, biologic, and biochemical abnormalities caused by a dysregulated host response to infection. Sepsis and the inflammatory response that ensues can lead to multiple organ dysfunction syndrome and death.

  7. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Evidence of organ dysfunction includes clinical and laboratory abnormalities of the respiratory system, coagulation, liver, cardiovascular system, nervous system, and kidneys ( Table 79–1 ).

  8. Feb 3, 2023 · Bacterial sepsis is a clinical term used to describe symptomatic bacteremia, with or without organ dysfunction. Currently, sepsis is commonly defined as the presence of infection in conjunction with the systemic inflammatory response syndrome (SIRS), with severe sepsis understood as sepsis complicated by organ dysfunction and septic shock und...

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