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  2. Clarithromycin was developed in 1980 and approved for medical use in 1990. It is on the World Health Organization's List of Essential Medicines. Clarithromycin is available as a generic medication. It is made from erythromycin and is chemically known as 6-O-methylerythromycin.

  3. Mar 9, 2018 · Clarithromycin is a macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.

  4. Mar 22, 2024 · Warnings. Before taking. Dosage. Side effects. Interactions. FAQ. What is clarithromycin? Clarithromycin is a macrolide antibiotic that fights bacteria in your body. Clarithromycin is used to treat many different types of bacterial infections affecting the skin and respiratory system.

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  5. Clarithromycin is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the ears, sinuses, skin, and throat.

  6. Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection.

  7. The penetration of clarithromycin into the human tissues has been reviewed and the mean peak concentration of clarithromycin is 1.09, 0.07, and 0.08 µg/ ml in plasma, subcutaneous adipose tissue, and in skeletal muscle, respectively.

  8. Clarithromycin is primarily metabolised by cytochrome P450 (CYP) 3A isozymes and has an active metabolite, 14-hydroxyclarithromycin. The reported mean values of total body clearance and renal clearance in adults have ranged from 29.2 to 58.1 L/h and 6.7 to 12.8 L/h, respectively.

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