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  1. An estimated 4.4 percent of the global population has depression, according to a report released by the UN World Health Organization (WHO), which shows an 18 percent increase in the number of people living with depression between 2005 and 2015.

  2. Medication. Antidepressants. Frequency. 163 million (2017) [8] Major depressive disorder ( MDD ), also known as clinical depression, is a mental disorder [9] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities.

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  4. Background. Major depression (also called "major depressive disorder", "clinical depression" or often simply "depression") is a leading cause of disability worldwide, and in 2000 was the fourth leading contributor to the global burden of disease (measured in DALYs ); it is also an important risk factor for suicide. [1]

  5. Oct 5, 2015 · From the earliest medical texts in ancient Greece to the present Diagnostic and Statistical Manual of Mental Disorders (DSM), deep sadness and its variants—hopelessness, sorrow, dejection, despondency, emptiness, despair, discouragement—have been mentioned as core features of depression.

  6. Mar 5, 2021 · The biology of depression is incompletely known, and much of it may remain permanently elusive. But the idea that depression is purely psychological is, I think, implausible. But so is the view that depression is purely biological. The dichotomy itself is the problem. Mark Solms, PhD, says that mind and brain are 2 ways of looking at the same ...

  7. Oct 14, 2022 · Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive disorder or clinical depression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems.

  8. Mar 27, 2023 · Hippocrates, a Greek physician, suggested that depression (initially called "melancholia") was caused by four imbalanced body fluids called humours: yellow bile, black bile, phlegm, and blood. Specifically, he thought that melancholia was caused by too much black bile in the spleen. Hippocrates' treatments of choice included bloodletting, baths ...

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