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- Season 1 overviewOct 6, 2000-May 17, 200123 episodesSeason 1 episodes1. Pilot Oct 6, 2000
- Investigation team works in Las Vegas; murderer makes acts look like suicides.
- 2. Cool Change Oct 13, 2000
- Someone is murdering people who have won millions on slot machines.
- 3. Crate 'n Burial Oct 20, 2000
- A multimillionaire's wife is kidnapped; a young girl is the victim of a hit-and-run.
- 4. Pledging Mr. Johnson Oct 27, 2000
- Grissom and Catherine investigate the death of woman found in lake.
- 5. Friends and Lovers Nov 3, 2000
- Grissom and Warrick investigate death of young man found the desert.
- 6. Who Are You? Nov 10, 2000
- Grissom and Nick must identify a young woman, then find her killer.
- 7. Blood Drops Nov 17, 2000
- A quadruple homicide shatters the serenity of a quiet suburban neighborhood.
- 8. Anonymous Nov 24, 2000
- A serial killer begins leaving clues to taunt Grissom; Warrick and Nick clash.
- 9. Unfriendly Skies Dec 8, 2000
- A first-class passenger dies on a plane, and Grissom's team must find the cause.
- 10. Sex, Lies and Larvae Dec 22, 2000
- Grissom and Sara investigate a homicide in the mountains; Catherine and Warrick probe a theft.
- 11. I-15 Murders Jan 12, 2001
- Grissom and Willows hunt down the Highway I-15 serial killer.
- 12. Fahrenheit 932 Feb 1, 2001
- Grissom is called to help a man on death row who is trying to clear his name.
- 13. Boom Feb 8, 2001
- Grissom, Sara and Warrick investigate the bombing of an office building.
- 14. To Halve and to Hold Feb 15, 2001
- Grissom and Catherine search for human remains in the desert.
- 15. Table Stakes Feb 22, 2001
- The team examines the case of a corpse found floating in a pool; Warrick investigates a mob hit.
- 16. Too Tough to Die Mar 1, 2001
- The team investigates a sexual assault; Catherine and Warrick help the D.A.
- 17. Face Lift Mar 8, 2001
- A robbery/homicide with a missing suspect; the case of a woman burned to ashes.
- 18. $35K O.B.O. Mar 29, 2001
- The team visits the site of a fatal car-jacking and realizes rain washed away evidence.
- 19. Gentle, Gentle Apr 12, 2001
- In a case of infant kidnapping, the team finds clues that point to an unthinkable conclusion.
- 20. Sounds of Silence Apr 19, 2001
- The CSI team investigates a vehicular fatality; Catherine and Nick look into a multiple homicide.
- 21. Justice Is Served Apr 26, 2001
- Catherine tries to determine the cause of death of a little girl on a carnival ride.
- 22. Evaluation Day May 10, 2001
- The CSI team investigates a decapitated corpse; a murder takes place in a juvenile detention center.
- 23. The Strip Strangler May 17, 2001
- The CSI team and the FBI investigate the serial strangling of young women in Las Vegas.