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  2. Feb 12, 2024 · Bicarbonate tablets are available as 650 mg NaHCO 3, 25 to 50 mEq KHCO 3, 20 to 40 mEq KHCO 3-citric acid, and 20 to 50 mEq KHCO 3-KCl tablets. [10] In patients with arrhythmias and cardiovascular instability, sodium bicarbonate can be administered to adults with 4 to 8-hour IV infusions.

    • Usual Adult Dose For Metabolic Acidosis
    • Usual Adult Dose For Diabetic Ketoacidosis
    • Usual Adult Dose For Urinary Alkalinization
    • Usual Adult Dose For Hyperkalemia
    • Usual Adult Dose For Asystole
    • Usual Pediatric Dose For Metabolic Acidosis
    • Usual Pediatric Dose For Urinary Alkalinization
    • Usual Pediatric Dose For Hyperuricemia Secondary to Chemotherapy
    • Usual Pediatric Dose For Asystole
    • Renal Dose Adjustments

    Parenteral: If acid-base status is available, dosages should be calculated as follows: 0.2 x weight (kg) x base deficit. Alternatively: HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)]. or Moderate metabolic acidosis: 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour d...

    Although sodium bicarbonate is approved for the treatment of metabolic acidosis, data have shown that the use of this drug may be harmful in certain clinical settings such as lactic acidosis, acidosis with tissue hypoxia, uremia, severe cardiac dysfunction or arrest, and diabetic ketoacidosis. Most experts only allow for its use when tissue perfusi...

    Parenteral: 50 to 150 mEq sodium bicarbonate diluted in 1 L of D5W to be intravenously infused at a rate of 1 to 1.5 L/hour. Oral: 325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmoL) each of sodium and bicarbonate. The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to increase the renal excr...

    One ampule of 7.5% sodium bicarbonate (44.6 mEq HCO3 ion) may be administered slowly IV over 5 minutes and repeated at 10 to 15 minute intervals if ECG changes persist. The onset of action occurs within 30 minutes and the effect lasts for 1 to 2 hours. The resultant effect restores intracellular potassium levels to normal without decreasing total b...

    1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient's acid-base status.

    If acid-base status is available, dosages should be calculated as follows: Infants and Children: HCO3 (mEq) required = 0.3 x weight (kg) x base deficit (mEq/L) OR HCO3 (mEq) required = 0.5 x weight (kg) x [24 - serum HCO3 (mEq/L)]. If acid-base status is not available, dosages should be calculated as follows: Older children: 2 to 5 mEq/kg IV infusi...

    0 to 12 years: 1 to 10 mEq (84 to 840 mg)/kg/day orally in divided doses; dose should be titrated to desired urinary pH. Greater than 12 to 18 years: 325 to 2000 mg orally 1 to 4 times a day. One gram provides 11.9 mEq (mmol) each of sodium and bicarbonate. The goal of therapy is to correct serum pH and increase the urinary pH to 8 in order to incr...

    0 to 12 years: Parenteral: 120 to 200 mEq/m2/day diluted in maintenance IV fluids of 3000 mL/m2/day; titrate to maintain urine pH between 6 and 7. Oral: 12 g/m2/day divided into 4 doses; titrate to maintain urine pH between 6 and 7.

    1 mEq/kg slow IV initially, may repeat with 0.5 mEq/kg 10 minutes later one time, or as indicated by the patient acid-base status.

    Due to the risk of hypernatremia, electrolyte shifts, and systemic pH changes, it is recommended that sodium bicarbonate be used with caution due to this patient's renal dysfunction. Close monitoring of this patient's plasma electrolytes and bicarbonate is recommended, particularly if dose increments are considered.

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  3. Feb 12, 2024 · Bicarbonate tablets are available as 650 mg NaHCO 3, 25 to 50 mEq KHCO 3, 20 to 40 mEq KHCO 3-citric acid, and 20 to 50 mEq KHCO 3-KCl tablets. [10] In patients with arrhythmias and cardiovascular instability, sodium bicarbonate can be administered to adults with 4 to 8-hour IV infusions.

  4. Apr 10, 2024 · Initially, 2036 mEq daily, given in divided doses when plasma bicarbonate concentration is less than 15 mEq/L. Titrate dosage to provide a plasma bicarbonate concentration of about 18–20 mEq/L. To relieve symptoms and prevent or stabilize renal failure and osteomalacia in patients with renal tubular acidosis, higher dosages of sodium ...

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  5. Oct 10, 2020 · It can be due to diarrhea, ileostomy output, enterocutaneous fistulas, or short bowel syndrome where a significant amount of bicarbonate from pancreatic secretions can be lost in the stool. The kidney compensates by reabsorbing bicarbonate and increasing acid excretion rapidly.

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  6. Feb 17, 2020 · Mechanism of Action. Dissociates to provide bicarbonate ion which neutralizes hydrogen ion concentration and raises blood and urinary pH. Neutralizing additive (dental use): Increases pH of lidocaine and epinephrine solution to improve tolerability and increase tissue uptake.

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