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How is von Willebrand disease treated?
What happens if you have von Willebrand disease?
What is von Willebrand disease (vWD)?
Oct 26, 2021 · Many doctors consider desmopressin (DDAVP) the first treatment for managing von Willebrand disease. It can be used before minor surgical procedures to help control bleeding. You might be given a trial of desmopressin to make sure it's effective for you.
- What Is Von Willebrand Disease?
- What Happens If You Have Von Willebrand Disease?
- How Common Is This condition?
von Willebrand disease is a common blood disorder that keeps your blood from clotting. This is an inherited disorder, meaning parents may pass the disorder on to their biological children. Healthcare providers treat this disorder with medication to help with blood clotting.
People with von Willebrand disease may bleed more than usual. For example, they may have frequent nosebleeds or bleed for a long time after getting a minor cut. Women or people designated female at birth (DFAB) may have heavy menstrual periods or heavy bleeding after giving birth. People who have the most serious form of von Willebrand disease may ...
von Willebrand disease affects 1% of the U.S. population and is the most common bleeding disorder in the United States. Globally, von Willebrand disease affects an estimated 23 to 110 in 1 million people. The numbers vary because people may have bleeding issues, but aren’t diagnosed with von Willebrand disease. In some cases, people have had bleedi...
Jan 12, 2021 · Major therapies include use of desmopressin to induce endothelial release of stored von Willebrand factor (VWF) and factor VIII (FVIII) and use of VWF concentrates, including both plasma-derived and recombinant products, as well as adjuvant therapies, such as antifibrinolytic tranexamic acid.
- Nathan T. Connell, Veronica H. Flood, Romina Brignardello-Petersen, Rezan Abdul-Kadir, Alice Arapshi...
- 2021
Aug 28, 2023 · Treatment / Management. Stable patients with type 1, some type 2 (except type 2B), and acquired von Willebrand disease patients are given a trial of desmopressin (DDAVP), which is a synthetic analog of vasopressin to check for a response. This is usually performed when patients are not actively bleeding.
- Ayan Sabih, Hani M. Babiker
- 2023/08/28
- 2019
The panel recommends a VWF activity level1 of <0.30 IU/mL regardless of bleeding, and in patients with abnormal bleeding, a VWF level of <0.50. 3 IU/mL2 to confirm the diagnosis of type 1 VWD. . VWF level(s) refers to VWF:Ag and/or platelet-dependent VWF activity (e.g., VWF:GPIbM).
Blood Adv. 2021;5(1):301-325. PANEL FORMATION. Each guideline panel was formed following these key criteria: Balance of expertise (including disciplines beyond hematology, and patients) Close attention to minimization and management of COI. CLINICAL QUESTIONS. 10 to 20 clinically-relevant questions.
