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  1. The Oprah Winfrey Show, often referred to as The Oprah Show or simply Oprah, is an American daytime syndicated talk show that aired nationally for 25 seasons from September 8, 1986, to May 25, 2011, from Chicago, Illinois.

  2. Mar 21, 2024 · Oprah Winfrey is sharing some of the powerful lessons she learned after hosting a TV special on Monday night about obesity and the growing popularity of weight-loss drugs.

    • 3 min
    • A. Pawlowski
  3. Watch The Oprah Winfrey Show episodes online or through the OWN app today! The Oprah Winfrey Show was the number one talk show for 24 consecutive seasons.

  4. Mar 19, 2024 · The special, which will be available on Hulu starting March 19, spotlights a class of drugs known as GLP-1 agonists, which mimic a hormone that suppresses appetite and controls blood sugar ...

  5. Find out how to watch The Oprah Winfrey Show. Stream the latest seasons and episodes, watch trailers, and more for The Oprah Winfrey Show at TV Guide.

    • Oprah Winfrey
    • 23
  6. Mar 18, 2024 · Oprah Winfrey hosts a sit-down conversation around the radical impact of prescription weight loss medications in the primetime event, "An Oprah Special: Shame, Blame and the Weight Loss Revolution," airing MONDAY, MARCH 18 (8:00-9:00 p.m. EDT), on ABC and the next day on Hulu.

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  8. The Oprah Winfrey Show: With Oprah Winfrey, Nate Berkus, Gayle King, Chris Rock. Oprah Winfrey hosts a live audience talk-show with celebrity guests and discusses daily stories.

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