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Enterobacteria phage T4. Escherichia virus T4 is a species of bacteriophages that infect Escherichia coli bacteria. It is a double-stranded DNA virus in the subfamily Tevenvirinae from the family Myoviridae. T4 is capable of undergoing only a lytic life cycle and not the lysogenic life cycle.
- Escherichia virus T4
- Tequatrovirus
Figure 2. The structure of the bacteriophage T4 head. The symmetry of the gp23* major capsid protein shell is characterized by triangulation numbers T end = 13 laevo and T mid = 20 (h 1 = 3, k 1 = 1, h 2 = 4 and k 2 = 2) [ 26, 27 ]. The facet triangles are shown in green and the basic triangles are shown in black.
- Moh Lan Yap, Michael G Rossmann
- 10.2217/fmb.14.91
- 2014
- 2014/10
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Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of tailed phages. T4 assembly is divided into three independent pathways: the head, the tail and the long tail fibers. The prolate head encapsidates a 172 kbp concatemeric dsDNA genome. The 925 Å-long tail is surrounded by the contractile sheath and ends ...
Anatomy and infection cycle of bacteriophage T4. A bacteriophage ( / bækˈtɪərioʊfeɪdʒ / ), also known informally as a phage ( / ˈfeɪdʒ / ), is a virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ( phagein ), meaning "to devour".
Feb 14, 2023 · Abstract. Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal vertex, and genome packaging add a significant body of new literature to phage biology. Head structures in unexpanded and expanded conformations show dramatic ...
- 10.3390/v15020527
- 2023/02
- Viruses. 2023 Feb; 15(2): 527.
Dec 24, 2022 · T-4 bacteriophage is a bacteriophage that infects E. coli bacteria. Its double-stranded DNA genome is about 169 kbp long and is held in an icosahedral head, also known as a capsid. T4 is a relatively large phage, at approximately 90 nm wide and 200 nm long (most phages range from 25 to 200 nm in length). Its tail fibres allow attachment to a ...
May 19, 2016 · Bacteriophage T4 uses its contractile tail to inject its genome into a bacterial host cell. Central to this process is the baseplate, at the end of the tail. In a tour-de-force of structural ...