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  1. Fixed drug eruption typically presents as a single (or small number of) well-defined, round or oval red or violaceous patch or plaque which may blister or ulcerate. It is usually asymptomatic but can be itchy or painful.

  2. Apr 8, 2024 · Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re-exposure to the offending drug. Acute FDE usually presents with a single or a small number of dusky red or violaceous plaques that resolve leaving postinflammatory hyperpigmentation ( picture 1A-C ).

  3. Sep 1, 2021 · Fixed drug eruption (FDE) is a cutaneous adverse drug reaction characterized by the onset of rash at a fixed location on the body each time a specific medication is ingested. With each recurrence, the eruption can involve additional sites.

  4. Oct 9, 2020 · The term fixed drug eruption (FDE) describes the development of one or more annular or oval erythematous patches as a result of systemic exposure to a drug;...

  5. Fixed drug eruption (FDE) is a well-defined, circular, hyperpigmenting plaque that recurs as one or a few lesions always in fixed locations upon ingestion of a drug. FDE commonly occurs on the genitals, lips, trunk, and hands.

  6. Apr 10, 2023 · Fixed pigmented erythema (FPE), also known as a fixed drug eruption, occurs 24 hours to a few days after administration of the offending medication. The classic form is characterized by a single or multiple round to oval-shaped, red to brown macules.

  7. Aug 23, 2022 · Fixed drug eruptions (FDEs) are dermatological manifestations of drug reactions that often occur in the same location upon re-exposure to a drug. They usually appear as erythematous-violaceous, circular patches, but several different variants have been described.

  8. A fixed drug eruption (FDE) is a relatively common reaction associated with more than 100 medications. It is defined as a same-site recurrence with exposure to a particular medication.

  9. Oct 9, 2022 · A fixed drug eruption (FDE) is a common cutaneous adverse drug reaction which occurs following administration of an offending drug. The aim of this review is to provide an update on the list of drugs causing FDE, with a focus on emerging drug culprits reported since the start of the century.

  10. Fixed drug eruption (FDE) is a distinctive type of cutaneous drug reaction that characteristically recurs in the same locations upon re-exposure to the offending drug. When fixed drug eruptions are … Erythema multiforme: Pathogenesis, clinical features, and diagnosis. …associated with EM Unlike EM, medication is the most frequent cause of SJS.

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