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      • The oil is named for Lorenzo Odone, a 5-year-old who started showing signs of ALD in 1983. His parents, Augusto and Michaela, were frustrated by the lack of treatment options. Despite having no medical training, they set out to find a treatment. They developed the oil in 1986.
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  2. Lorenzo's Oil is a 1992 drama film directed and co-written by George Miller. It is based on the true story of Augusto and Michaela Odone, parents who search for a cure for their son Lorenzo's adrenoleukodystrophy (ALD), leading to the development of Lorenzo's oil.

  3. Jul 21, 2004 · Lorenzo's oil: The full story. Lorenzo Odone is 25 years old and lives in Washington. Eighteen years ago he was diagnosed with an incurable disease and given less than two years to...

  4. Oct 30, 2013 · When the oil was first given to Lorenzo, his VLCFA levels reduced rapidly from very high to normal. Lorenzo survived until age 30, far longer than his original prognosis. The oil did not seem to reverse any of his neurological deficits, but did seem to slow progression.

  5. Dec 22, 2021 · Lorenzo’s oil was introduced in 1989 for the treatment of ALD ( 4 ). ALD is a progressive neurodegenerative disorder that occurs in children. It’s caused by a genetic mutation that prevents the...

  6. Lorenzo’s Oil did not cure Lorenzo Odone, the couple’s son, who died in 2008 at age 30 from a rare neurological disease known as adrenoleukodystrophy, or ALD. But the movie, directed by...

  7. Nov 1, 2013 · With the help of a team of scientists, Odone and his wife eventually developed a chemical compound known as Lorenzos Oil which seemed to slow Lorenzos disease.

  8. History. Failing to find a doctor capable of treating their young son Lorenzo’s rare disease, Augusto and Michaela Odone, founders of The Myelin Project, sought their own cure. They set out on a mission to find a treatment to save their child.

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