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Persistent unexplained fever despite basic investigation
- Pyrexia of unknown origin (PUO), also known as fever of unknown origin (FUO), is a grouping of many unrelated medical conditions that share the feature of persistent unexplained fever despite basic investigation.
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Aug 14, 2023 · Fever of unknown origin (FUO) was first described by Dr. Petersdorf and Dr. Beesom in 1961.[1] FUO was defined as a temperature of 101 degrees Fahrenheit (38.3 degrees Centigrade) or higher with a minimum duration of three weeks without an established diagnosis despite at least one week's investigation in the hospital.
Nov 28, 2023 · Fever of unknown origin (FUO) is a prolonged febrile illness without an established etiology despite intensive evaluation and diagnostic testing. Learn about the definitions, categories, and diagnostic approach to FUO in adults from UpToDate, a clinical reference resource.
FUO is body temperature ≥ 38.3° C (≥ 101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or abnormalities on common tests. Learn about the etiology, evaluation, and treatment of FUO and its categories.
- Larry M. Bush
Sep 16, 2016 · Pyrexia of unknown origin (PUO) is a syndrome that has long tested the skills of physicians to achieve a diagnosis in affected patients. By definition, patients included in this syndrome will be more difficult to diagnose as they have already resisted classification during baseline investigations.
- Robyn W Beresford, Iain B Gosbell, Iain B Gosbell
- 2016
Apr 10, 2017 · Key features of fever of unknown origin (FUO), also known as pyrexia of unknown origin (PUO), are as follows: Unexplained fevers are worrisome to patients and clinicians, but most...
Sep 15, 2023 · of unknown origin (FUO) is defined as a temperature of > 38.3°C (100.9°F) lasting for > 3 weeks with no clear etiology despite appropriate diagnostics. Infections, malignancy. , and inflammatory or rheumatic conditions are the most frequent etiologies of FUO.
