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Sep 22, 2015 · September 22, 2015. DEAR MAYO CLINIC: Every few weeks my toddler will develop a fever that lasts a couple of days but then goes away. Other than the fever, she doesn’t have any other symptoms. Could it be periodic fever syndrome? How is that diagnosed, and is treatment for it different than treating a “normal” fever in kids?
- What Are Periodic Fever Syndromes (Now Known as Recurrent Fever Syndromes)?
- Is Recurrent Fever Syndrome Common?
- What Are Some of The Different Types of Recurrent Fever Syndrome?
Recurrent fever syndromes, formerly known as periodic fever syndromes, are a group of disorders that cause recurrent fevers that don’t have an infectious (virus, bacteria) cause. The syndromes are considered autoinflammatory diseases, which means an abnormality or regulation problem in your child’s natural (innate) immune system causes the conditio...
There are several different types of recurrent fever syndrome. For some types, the frequency (how often someone has the condition) is unknown. For others, the frequency is increasing because researchers have discovered a variety of mutations that cause the syndromes. Most are very rare, but some are more common than others. For instance, tumor necr...
Familial Mediterranean fever
Familial Mediterranean fever (FMF) is the most common genetically diagnosed recurrent fever syndrome. It causes recurrent fevers and may cause painful inflammationin your child’s abdomen, chest and joints. With FMF, the attacks typically begin in childhood. As your child ages, the frequency and severity of their attacks may become less intense.
Periodic fever, aphthous-stomatitis, pharyngitis, adenitis
Periodic fever, aphthous-stomatitis, pharyngitis, adenitis (PFAPA) includes periodic fevers with mouth sores (aphthous stomatitis), sore throat (pharyngitis) and swollen lymph nodes(adenitis) in your child’s neck. PFAPA affects children in early childhood, usually starting before 4 years old. Episodes usually decrease in frequency and resolve after age 10.
Tumor necrosis factor receptor-associated periodic syndrome
Apart from episodes of fever, tumor necrosis factor receptor-associated periodic syndrome (TRAPS) may cause abdominal pain, diarrhea, spreading skin rashes, muscle painand swelling around your child’s eyes. TRAPS may first appear during early to late childhood or into adulthood. The former name of this syndrome was familial Hibernian fever.
To provide an approach to recurrent fever in childhood, explain when infections, malignancies, and immunodeficiencies can be excluded, and describe the features of periodic fever and other autoinflammatory syndromes.
- Gordon S Soon, Ronald M Laxer
- Can Fam Physician. 2017 Oct; 63(10): 756-762.
- 2017
- 2017/10
Jun 21, 2021 · The Food and Drug Administration (FDA) recommends contacting a doctor if a toddler experiences a fever of 102ºF (38.8ºC) or more. A parent of caregiver should also contact a doctor if the...
Feb 15, 2003 · Recurrent fevers are defined as three or more febrile episodes in a six-month period, occurring at least seven days apart, with no causative medical illness. These episodes can occur at regular...
Mar 25, 2016 · Most children with recurrent fever have self-limited, common illnesses due to the physiological susceptibility to infections typical of the pediatric age group and will have a favorable prognosis. In a minority of cases, the cause of recurrent fever is a more rare disease that requires second line investigations and specific treatment.
People also ask
Why does my toddler have a fever?
What causes recurrent fevers in children?
How do I know if my toddler has a fever?
For acute recurrent or periodic fever, laboratory tests and imaging should be directed toward likely causes based on findings from the history and physical examination. PFAPA syndrome should be considered in young children who have periodic high fever at intervals of about 3 to 5 weeks with aphthous ulcers, pharyngitis, and/or adenitis. Between ...
