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  1. Oct 30, 2019 · Travelers to parts of the world where typhoid is common. (NOTE: typhoid vaccine is not 100% effective and is not a substitute for being careful about what you eat or drink.) People in close contact with a typhoid carrier. Laboratory workers who work with Salmonella typhi bacteria. Typhoid vaccine may be given at the same time as other vaccines.

    • RTF [4 Pages]

      One is an inactivated (killed) vaccine and the other is a...

  2. Sep 30, 2010 · Vaccines Recommended for Travel and Some Specific Groups. If you are traveling to a country where typhoid ( Salmonella serotype Typhi) is common, you should consider being vaccinated against typhoid. Visit a doctor or travel clinic to discuss your vaccination options. Remember that you will need to complete your vaccination at least 1 week ...

    • Ty21a
    • Repeat Doses
    • Acknowledgments
    • References

    Primary vaccination with live-attenuated Ty21a vaccine consists of one enteric-coated capsule taken on alternate days (day 0, 2, 4, and 6), for a total of four capsules. The capsules must be kept refrigerated (not frozen). Each capsule should be taken with cool water no warmer than 98.6°F (37.0°C), approximately 1 hour before a meal. All doses shou...

    If continued or repeated exposure to Salmonella serotype Typhi is expected, repeat doses of typhoid vaccine are needed to maintain immunity (Table). An optimal revaccination schedule for the Vi polysaccharide vaccine has not been established; however, the manufacturer recommends a repeat dose every 2 years after the primary dose if continued or ren...

    ACIP members (membership roster for July 2014–June 2015 available at http://www.cdc.gov/vaccines/acip/committee/members.html. 1Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, CDC; 2Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infecti...

    CDC. CDC health information for international travel 2014. Available at http://wwwnc.cdc.gov/travel/page/yellowbook-home-2014.
    Stuart BM, Pullen RL. Typhoid; clinical analysis of 360 cases. Arch Intern Med (Chic) 1946;78:629–61.
    Bhan MK, Bahl R, Bhatnagar S. Typhoid and paratyphoid fever. Lancet 2005;366:749–62.
  3. Typhoid vaccines are safe and effective and were recommended by WHO for typhoid control in 2000 and 2007, with prioritised immediate implementation in 2009. In 2018, WHO sanctioned the administration of TCV to children in endemic countries, especially those with a high burden of drug-resistant S Typhi.

  4. Jan 25, 2024 · A single dose of Vi-TT is durably efficacious for at least 4 years among children aged 9 months to 12 years and shows efficacy in all age groups, including children younger than 2 years. These results support current WHO recommendations in typhoid-endemic areas for mass campaigns among children aged 9 months to 15 years, followed by routine introduction in the first 2 years of life.

  5. Jun 6, 2014 · 1. Introduction. Typhoid vaccination is recommended in the United States before travel to countries where typhoid fever is endemic [1–3].Two vaccines are available – live, oral Ty21a (Vivotif ®, Crucell/Berna) and typhoid Vi polysaccharide (Typhim Vi ®, Sanofi Pasteur) – but little information exists on their effectiveness in travelers.

  6. We excluded any cases of typhoid fever that occurred less than 28 days after vaccination from the calculation of vaccine effectiveness. Vaccine effectiveness, with 95% CIs, against culture-confirmed, culture-negative suspected, and XDR S Typhi was calculated as follows: 100 × (1–IRR).

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