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  1. May 15, 2024 · A combination of blood tests is needed to diagnose von Willebrand disease (VWD). The following screening tests are done first to show if the blood is clotting properly. These tests may suggest a possible bleeding disorder, but more tests are needed to tell the type of bleeding disorder present. Screening tests are often normal in VWD, and more ...

    • What Is Von Willebrand Disease?
    • What Happens If You Have Von Willebrand Disease?
    • How Common Is This condition?

    von Willebrand disease is a common blood disorder that keeps your blood from clotting. This is an inherited disorder, meaning parents may pass the disorder on to their biological children. Healthcare providers treat this disorder with medication to help with blood clotting.

    People with von Willebrand disease may bleed more than usual. For example, they may have frequent nosebleeds or bleed for a long time after getting a minor cut. Women or people designated female at birth (DFAB) may have heavy menstrual periods or heavy bleeding after giving birth. People who have the most serious form of von Willebrand disease may ...

    von Willebrand disease affects 1% of the U.S. population and is the most common bleeding disorder in the United States. Globally, von Willebrand disease affects an estimated 23 to 110 in 1 million people. The numbers vary because people may have bleeding issues, but aren’t diagnosed with von Willebrand disease. In some cases, people have had bleedi...

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  3. Dec 22, 2018 · Von Willebrand factor (vWF or VWF) is a protein that is one of several components of the coagulation system that work together, and in sequence, to stop bleeding within the body. VWF testing measures the amount of the protein present in blood and determines how well the protein functions.

  4. Nov 22, 2023 · Von Willebrand disease (VWD) is a blood-clotting disorder. It occurs when a person has insufficient or ineffective supplies of a substance in the blood known as von Willebrand factor (VWF).

  5. Apr 16, 2024 · von Willebrand disease (VWD) is a bleeding disorder. It can be inherited or, less commonly, it can develop later in life (this type of VWD is not heritable and is referred to as acquired von Willebrand syndrome [AVWS]). The amount of bleeding and need for treatment varies from person to person, with some never needing treatment (or even knowing ...

  6. Jul 23, 2023 · Von Willebrand disease (VWD) causes excessive bleeding due to a defective or reduced amount of von Willebrand factor, a protein involved in blood clotting. This bleeding disease is nearly always inherited and commonly linked to heavy or prolonged menstrual bleeding, spontaneous nosebleeds, easy bruising, and extended bleeding after a minor cut ...

  7. von Willebrand disease (vWD) should be considered in the differential diagnosis of any case where a patient with bleeding history has a normal protime (PT) and activated partial thromboplastin time (aPTT). The aPTT can be extended in severe vWD due to diminished levels of factor VIII that result from inadequate vWF binding. 6.

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