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- Prevalence Von Willebrand disease (VWD) occurs with equal frequency among men and women, affecting up to 1% of the general population. 1 2 However, women are more likely to experience symptoms of VWD because of the increased bleeding it causes during their menstrual periods, during pregnancy, and after childbirth.
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Prevalence. Von Willebrand disease (VWD) occurs with equal frequency among men and women, affecting up to 1% of the general population. 1 2 However, women are more likely to experience symptoms of VWD because of the increased bleeding it causes during their menstrual periods, during pregnancy, and after childbirth.
Oct 16, 2023 · Von Willebrand disease (VWD) is a common bleeding disorder caused by mutations in the von Willebrand factor gene (VWF). The true global prevalence of VWD has not been accurately established.
Oct 16, 2023 · The true global prevalence of VWD has not been accurately established. We estimated the worldwide and within-population prevalence of inherited VWD by analyzing exome and genome data of 141,456 individuals gathered by the genome Aggregation Database (gnomAD).
- 10.1038/s41525-023-00375-8
- 2023
- NPJ Genom Med. 2023; 8: 31.
The prevalence of VWD based on abnormal laboratory parameters alone is approximately 1 in 100, while the clinical prevalence, taking into consideration only those patients with bleeding symptoms, is likely closer to 1 in 1000 ( 9, 10, 11 ). VWD is inherited in an autosomal manner so males and females are affected equally.
- Angela C. Weyand, Veronica H. Flood
- 2021/12
- 10.1016/j.hoc.2021.07.004
Mar 2, 2023 · Reported VWD prevalence (22 sources) ranged from 108.9 to 2200 per 100,000 in population-based studies and from 0.3 to 16.5 per 100,000 in referral-based studies. Reported times between first symptom onset and diagnosis (two sources; mean 669 days; median 3 years) highlighted gaps in timely VWD diagnosis.
Von Willebrand Disease is a blood disorder in which the blood does not clot properly. Skip directly to site content Skip directly to search An official website of the United States government
Specialty. Hematology. Von Willebrand disease ( VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion.
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