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The genesis of serology dates to the end of the 19 th century and the pioneering “serum therapy” of Emil von Behring and Paul Ehrlich, followed for decades by elegant studies on the specificity of serological reactions by Karl Landsteiner.
- PMC Free Article
Experiments are presented on the cross reactions of hen egg...
- Oligopeptide M13 Phage Display in Pathogen Research
1. M13 Phage Display. Phage display technology is a widely...
- Two Major Autoantibody Clusters in Systemic Lupus Erythematosus
Introduction. Systemic lupus erythematosis (SLE) is an...
- PMC Free Article
Sep 10, 2004 · Introduction. The starting point of forensic serology is – as the term already implies – the introduction of immunological techniques in the examination of stains and identification as well as paternity testing. The field specific immunological techniques are a phenomenon of the 20th century.
- D. Patzelt
- 2004
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May 9, 2018 · This method was discovered by the German biologist Paul Uhlenhunth in the late 1870s. He injected protein from a chicken egg into a sample of rabbit ’ s blood. After a few days, he extracted the rabbit ’ s serum and mixed it with egg white, causing the separation of egg proteins from the solution to form a whitish clotting substance, precipitin.
Serology / history* United States. Substances. ABO Blood-Group System. The events of three periods occurring during 1900-1980 are traced to illustrate the sources from which forensic serology evolved.
- Frank R. Camp
- 1980
Virological diagnosis. Serology: the diagnosis of measles is primarily clinical. Serological methods, such as haemagglutination inhibition, testing for IgG titre rise or detecting IgM, may be of value. Isolation: direct microscopy on respiratory cells can reveal giant cell formation and immunofluorescence microscopy on respiratory secretions ...
It was first used in evidence in a British court in 1986, ultimately proving the innocence of a 17-year-old man with learning difficulties who was a suspect in a double rape-murder case. Widespread DNA testing among the local community later identified the true killer who received a life sentence for his crimes.
Forensic serology is the examination of various physiological fluids, including blood, semen, saliva, urine, vomit, fecal matter, and perspiration (sweat), for judicial proceedings. The presumptive test is used to start the detection process since it suggests that a particular bodily fluid might be present, but the other confirmation test ...