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- The viruses that infected two people in Cambodia with H5N1 avian influenza have been identified as an endemic clade of bird flu circulating in the country, the U.S. Centers for Disease Control and Prevention (CDC) said.
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Feb 26, 2023 · Feb 26 (Reuters) - The viruses that infected two people in Cambodia with H5N1 avian influenza have been identified as an endemic clade of bird flu circulating in the country, the U.S....
Mar 3, 2023 · CDC has conducted a preliminary analysis of the genetic sequences of these H5N1 bird flu viruses. They are H5N1 viruses from clade 2.3.2.1c, which are different from the H5N1 viruses now spreading in U.S. wild birds and poultry, which are from clade 2.3.4.4b.
Feb 12, 2024 · Genetic sequencing of the first and third patients’ specimens by IPC and NIPH identified both H5N1 viruses as H5 clade 2.3.2.1c, which has circulated in Cambodia among birds and poultry for many years.
Feb 8, 2024 · Between 26 and 28 January 2024, the Cambodia National Focal Point (NFP) for the International Health Regulations (IHR) notified the World Health Organization (WHO) of two confirmed cases of human infection with avian influenza A (H5N1) virus.
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February 25, 2023 — Two human infections with avian influenza A H5N1 (H5N1 bird flu) virus have been reported by Cambodia. These cases are thought to be a result of exposure to infected birds/poultry. An investigation to try to confirm the source of the infections and detect any potential additional cases is ongoing. Based on preliminary genetic sequencing done in country, the Cambodian Ministry of Health has identified these viruses as being H5 clade 2.3.2.1c, which have circulated in Cambodia among birds/poultry for many years. These viruses have resulted in rare sporadic human infections in the past, but these two cases are the first such infections reported in Cambodia since 2014. The 2.3.2.1c viruses in Cambodia are different from H5N1 viruses currently circulating in wild birds and poultry in the United States and other countries, which are H5 clade 2.3.4.4b.
The cases in Cambodia occurred in a child, who died, and her father, who reported a fever and cough. No additional H5N1 cases have been identified at this time. To date, no indication of person-to-person spread has been found. There is no indication at this time that these two human cases of H5N1 in Cambodia pose a threat to the U.S. public.
The Cambodian Ministry of Health and other global public health officials are leading the investigation into these two human cases with support from in-country CDC staff and a CDC rapid response team. Investigation efforts include contact tracing, monitoring and/or testing of close contacts including health care workers who cared for the two patien...
For the United States, the ongoing outbreaks of 2.3.4.4b clade H5N1 bird flu in wild birds and poultry with sporadic spillover events into some mammals remains mainly an agricultural issue. The current risk to the general public from bird flu viruses remains low; however, it is important to remember that risk depends on exposure, and people with more exposure might have a greater risk of infection. People who have job-related or recreational exposures to infected birds or sick or dead mammals are at higher risk of infection and should take appropriate prevention measures. CDC also has guidance for clinicians on monitoring, testing, and antiviral treatment for patients with bird flu virus infections.
People should avoid contact with poultry, and wild birds and mammals that appear ill or are dead and avoid contact with surfaces that appear to be contaminated with feces from wild birds and mammals, or domestic poultry. Observe wild birds and mammals only from a distance, if possible. Wild birds and mammals can be infected with bird flu viruses without always appearing sick. If you must handle wild birds and mammals or sick or dead poultry, minimize direct contact by wearing gloves and wash your hands with soap and water after touching them. If available, wear respiratory protection such as a medical facemask and eye protection such as goggles.
The U.S. poultry industry has strict health and safety standards, including regular monitoring for bird flu. It is safe to eat properly handled and cooked poultry and poultry products in the U.S. The proper handling and cooking of poultry and eggs to an internal temperature of 165˚F kills bacteria and viruses, including H5 viruses.
The U.S. Department of Interior and USDA APHIS are the lead federal agencies for H5N1 in birds, poultry, and animals in the U.S. They are respectively responsible for outbreak investigation and control of bird flu in wild birds and in domestic poultry. CDC is the lead federal agency on the human health side.
CDC has been actively working on the domestic H5N1 situation since the initial detection of H5N1 in U.S. wild birds and poultry in early 2022. This includes preparing for the possibility that H5N1 viruses circulating in birds in the United States and in other countries gain the ability to easily infect and spread between people. This includes ensuring that there are prevention and treatment tools, in addition to testing capacity.
CDC’s existing influenza surveillance systems are well-equipped to rapidly detect cases of avian influenza A virus infection, including H5N1 virus, in people. CDC’s influenza virus tests, which can detect both seasonal and novel influenza A viruses, are used in all 50 U.S states and globally. Additionally, there are CDC diagnostic tests that specifically detect the current H5 viruses, which are available in public health laboratories in all 50 U.S. states and international laboratories.
Feb 27, 2023 · Over the weekend, Cambodia's health ministry announced that genetic analysis has revealed that the Asian clade 2.3.2.1c H5N1 avian influenza clade was involved in the two recent human infections, which involved an 11-year-old girl who died and her father who is still hospitalized.
Feb 27, 2023 · Updated. Feb 27, 2023, 10:23 PM. ATLANTA - The viruses that infected two people in Cambodia with H5N1 avian influenza have been identified as an endemic clade of bird flu circulating in...
