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May 28, 2020 · Escherichia coli is a rod-shaped (bacillus) Gram-negative bacterium that is frequently used as a model organism. Factors such as its ability to grow fast using cheap media and...
Mar 25, 2015 · However, research on E.coli has primarily examined it as a model organism, one that is abstracted from any natural history. But E. coli is far more than just a microbial lab rat. Rather, it is a highly diverse organism with a complex, multi-faceted niche in the wild.
- Zachary D Blount
- 2015
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Aug 2, 2022 · However, given the vast diversity among bacteria and even among E. coli strains, it was by many fortuitous events that E. coli rose to the top as an experimental model. Here, we share how serendipity and its own biology selected E. coli as the flagship bacterium of molecular biology.
Jul 12, 2017 · The main reasons why E. coli is the organism of choice extends and is not limited to its fast growth in chemically defined media; relative cheap culture media; does not form aggregates; industrial scalability; several molecular tools for manipulation; extensive knowledge of its genetics and genomics; extensive knowledge on its transcriptome ...
- Vargas-Maya Naurú Idalia, Franco Bernardo
- 2017
Mar 25, 2015 · By the 1940s, its use in many foundational studies firmly established E. coli as the bacterial model organism of choice, making it the obvious organism to work with at the onset of the molecular biology revolution in the 1950s.
Dec 31, 2022 · Escherichia coli have served as important model organisms for over a century—used to elucidate key aspects of genetics, evolution, molecular biology, and pathogenesis. However, defining which strains actually belong to this species is erratic and unstable due to shifts in the characters and criteria used to distinguish bacterial species.
Jul 5, 2023 · Model organisms are not perfect, and E. coli may not be an effective species to use to study many human bacterial infections. Focusing research on this microbe limits the exploration of how other...
