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      • 1 st MTP acute arthritis is highly prevalent in people with gout and has a substantial impact on patient-reported pain and disability. Gout affects the structure and function of the 1 st MTP. Microscopic and imaging studies have demonstrated crystal deposition and joint damage at the 1 st MTP in people with gout.
      bmcmusculoskeletdisord.biomedcentral.com › articles › 10
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  2. Feb 11, 2016 · Despite the well-recognised susceptibility of the 1 st MTP to acute arthritis in gout, evident by its inclusion in several gout diagnostic and classification criteria [7–10], a formal synthesis of the prevalence of acute 1 st MTP arthritis in this condition has yet to be undertaken.

    • Fig. 1

      The aim of this review was to qualitatively synthesise...

    • A Pilot Study

      Background. Gout is an inflammatory arthritis that occurs...

    • Arthritis / Acute Gout Attack
    • Chronic Tophaceous Gout
    • Asymptomatic Hyperuricemia
    • Diagnosis of Gout

    Gout is a form of arthritis, hence it causes pain and discomfort in the joints. A typical gout attack is characterized by the sudden onset of severepain, swelling, warmth, and redness of a joint. The clinical presentation of acute gouty arthritis is not subtle with very few mimics other than a bacterial infection. The joint most commonly involved i...

    Some patients only experience acute gout attacks which may be limited to 1-2 times per year (or even 1-2 times in lifetime). However, for some patients, gout can be a chronic, relapsing problem with multiple severe attacks that occur at short intervals and without complete resolution of inflammation between attacks. This form of gout, called chroni...

    It is important to recognize that although almost uniformly all patients with gout have hyperuricemia (high levels of uric acid in the blood)…all patients with hyperuricemia do not have gout. Although most patients will have elevated levels of uric acid in the blood for many years before having their first gout attack, there is no current recommend...

    A diagnosis of gout can be made with the documentation of the presence of uric acid crystals in synovial fluid or from a tophaceous deposit. In the setting of an acute gout attack, aspiration of joint fluid (by using a needle to draw fluid out of the swollen joint) and examination of the fluid under polarized light can yield the definitive diagnost...

  3. Gout with joint damage increases the risk of developing osteoarthritis. Coronary artery disease and metabolic syndrome are common in people with gout. Diagnosis of Gout

  4. Feb 11, 2016 · 1 (st) MTP acute arthritis is highly prevalent in people with gout and has a substantial impact on patient-reported pain and disability. Gout affects the structure and function of the 1 (st) MTP. Microscopic and imaging studies have demonstrated crystal deposition and joint damage at the 1 (st) MTP in ….

    • Sarah Stewart, Nicola Dalbeth, Alain C. Vandal, Keith Rome
    • 2016
  5. Nov 16, 2022 · Gout usually affects the big toe, but it can occur in any joint. Other commonly affected joints include the ankles, knees, elbows, wrists and fingers. The pain is likely to be most severe within the first four to 12 hours after it begins.

  6. Sep 22, 2015 · Gout most commonly affects the first metatarsophalangeal joint (1MTP). Existing theories suggest this may be related to the structure and functional role of the joint during gait, yet such characteristics of the 1MTP have not been investigated in people with gout or with AH.

  7. These x-rays may show punched-out lesions of subchondral bone with overhanging bony margins, most commonly in the 1st metatarsophalangeal joint; lesions must be ≥ 5 mm in diameter to be visible on x-ray. Joint space is typically preserved until very late in the course of disease.

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