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1. • • The future of sepsis biomarkers lies in extensive validation studies of such novel biomarkers across heterogeneous populations and exploration of their power in combination.
     Reference:

     Biomarkers of sepsis and their potential value in diagnosis ...

2. pubmed.ncbi.nlm.nih.gov › 37593782Biomarkers in Sepsis: A Current Review of New Technologies

   pubmed.ncbi.nlm.nih.gov › 37593782

   In this review, we will briefly describe the current consensus definitions of sepsis and the ideal features of a biomarker. We will then delve into currently available and in-development markers of pathogens, hosts, and their interactions that together comprise the sepsis syndrome.

   • An Update on Sepsis Biomarkers - PMC - National Center for ...

     In the future, we expect the development of angiopoietin as...

   • Advances in sepsis biomarkers - PubMed

     Sepsis, a dysregulated host immune response to an infectious...

3. People also ask

   Are sepsis biomarkers important?

   • Provided by the Springer Nature SharedIt content-sharing initiative Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic functions. In a previous review, we identified 3370 references reporting on 178 different biomarkers related to sepsis. In the present review, we evaluate the progress in the research of sepsis biomarkers.

   Biomarkers of sepsis: time for a reappraisal - Critical Care

   ccforum.biomedcentral.com/articles/10.1186/s13054-020-02993-5

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   What are the prognostic markers of sepsis?

   • The prognostic markers of sepsis are often involved in the organ dysfunction caused by sepsis and the development of therapeutic agents for sepsis targeting these prognostic biomarkers is being attempted. In addition, recent advances in technology have led to the development of new types of biomarkers such as the microbiome and non-coding RNAs.

   An Update on Sepsis Biomarkers

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7113456/

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   How many biomarkers are there in sepsis?

   • Forty-four biomarkers have been evaluated for a role in answering a specific clinical question rather than for their general diagnostic or prognostic properties in sepsis. The number of biomarkers being identified is still increasing although at a slower rate than in the past.

   Biomarkers of sepsis: time for a reappraisal - Critical Care

   ccforum.biomedcentral.com/articles/10.1186/s13054-020-02993-5

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   Does a sepsis biomarker predict mortality in septic patients?

   • Importantly, the majority of the studies that evaluated sepsis biomarkers using this method showed only a limited value; it seems highly unlikely that mortality in septic patients is related to only one pathophysiologic process that could be reflected by abnormal levels of a biomarker.

   Biomarkers of sepsis: time for a reappraisal - Critical Care

   ccforum.biomedcentral.com/articles/10.1186/s13054-020-02993-5

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4. ccforum.biomedcentral.com › articles › 10Biomarkers for sepsis: more than just fever and leukocytosis ...

   ccforum.biomedcentral.com › articles › 10

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   Jan 6, 2022 · For sepsis, a range of biomarkers is identified, including fluid phase pattern recognition molecules (PRMs), complement system, cytokines, chemokines, damage-associated molecular patterns (DAMPs), non-coding RNAs, miRNAs, cell membrane receptors, cell proteins, metabolites, and soluble receptors.

5. www.ncbi.nlm.nih.gov › pmc › articlesAn Update on Sepsis Biomarkers - PMC - National Center for ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Mar 26, 2020 · In the future, we expect the development of angiopoietin as a biomarker for predicting the diagnosis and prognosis of sepsis, but also the development of therapies for sepsis that target angiopoietin.

   • Author: Mi Hee Kim, Jung Hyun Choi
   • DOI: 10.3947/ic.2020.52.1.1

   • Publish Year: 2020
   • Publication: Infect Chemother. 2020 Mar; 52(1): 1-18.

6. ccforum.biomedcentral.com › articles › 10Biomarkers of sepsis: time for a reappraisal - Critical Care

   ccforum.biomedcentral.com › articles › 10

   • Cached

   Jun 5, 2020 · Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic functions. In a previous review, we identified 3370 references reporting on 178 different biomarkers related to sepsis. In the present review, we evaluate the progress in the research of sepsis biomarkers.

   • Author: Charalampos Pierrakos, Dimitrios Velissaris, Max Bisdorff, John C Marshall, Jean Louis Vincent

   • Publish Year: 2020

7. www.thelancet.com › journals › ebiomSepsis biomarkers and diagnostic tools with a focus on ...

   www.thelancet.com › journals › ebiom

   Dec 2, 2022 · The research highlighted here offers a number of potential future applications: these tools, in conjunction with routine clinical and biological information, may improve timeliness and accuracy of diagnosis, suggest physiological pathways and therapeutic targets, inform targeted recruitment into clinical trials, and optimise clinical management.

8. pubmed.ncbi.nlm.nih.gov › 38514209Advances in sepsis biomarkers - PubMed

   pubmed.ncbi.nlm.nih.gov › 38514209

   Sepsis, a dysregulated host immune response to an infectious agent, significantly increases morbidity and mortality for hospitalized patients worldwide. This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established sepsis biom ….

9. pubs.acs.org › doi › 10Rapid Detection of Sepsis: Recent Advances in Biomarker ...

   pubs.acs.org › doi › 10

   Nov 18, 2021 · The development of rapid sensing platforms that target sepsis-related biomarkers could significantly improve the outcomes of patients. This Mini-Review focuses on the recent advances in rapid diagnosis of soluble biomarkers in blood with the emphasis on different configurations of point-of-care (POC) instruments.