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  1. Feb 3, 2024 · Addison's disease, also called adrenal insufficiency, is an uncommon illness that occurs when the body doesn't make enough of certain hormones. In Addison's disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone. Addison's disease can affect anyone and can be life-threatening.

  2. Primary adrenal insufficiency. This is known as Addison's disease. It occurs when the adrenal glands are damaged. They don’t make enough of the hormones cortisol and aldosterone. This condition is rare. It may occur at any age. Secondary adrenal insufficiency. This starts when the pituitary gland doesn’t make enough of the hormone ACTH ...

  3. 3 days ago · Addison's disease is the result of the adrenal gland not producing enough hormones. Learn more about the symptoms, causes, and treatment here.

  4. Jul 6, 2022 · Addison’s disease is treated by replacing the missing hormones, cortisol and aldosterone, with synthetic versions of them. Cortisol is replaced by the drug hydrocortisone, and aldosterone is replaced by the drug fludrocortisone. Addison’s disease is a chronic condition, so you’ll need to take medication for the rest of your life.

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  6. Addison disease develops in approximately 4/100,000 people annually (1). It occurs in all age groups, about equally in each sex, and tends to become clinically apparent during metabolic stress, infection, or trauma. Adrenal crisis (onset of severe symptoms) may be precipitated by acute infection.

  7. Addison disease is usually due to a problem with your adrenal glands, including: An autoimmune disorder where your body’s immune system attacks your adrenal glands by mistake. Cancer of the adrenals . Infections of the adrenals, such as tuberculosis. Sometimes Addison disease is caused by a problem with your pituitary gland. Your pituitary ...

  8. Addison's disease, also known as primary adrenal insufficiency, [4] is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands ( adrenal cortex ), causing adrenal insufficiency. [5] [6] Symptoms generally come on slowly ...

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