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  1. Major Timothy Cain, simply known as Timothy Cain, is a major antagonist in the Resident Evil films, appearing as the overarching antagonist of the 2002 film Resident Evil and the main antagonist in the 2004 film Resident Evil: Apocalypse.

  2. Dr. Alexander Roland Isaacs is the main antagonist of the Resident Evil film series. He is the co-founder and supreme leader of the Umbrella Corporation, as well as the true mastermind behind the T-Virus apocalypse. Isaacs is the arch-nemesis of the series' protagonist Alice, as well as the film...

  3. Dr. Samuel "Sam" Isaacs is a major antagonist in the Resident Evil film series, serving as the overarching antagonist in the 2004 film Resident Evil: Apocalypse, the main antagonist in the 2007 film Resident Evil: Extinction and a minor antagonist in the 2016 film Resident Evil: The Final Chapter.

  4. Major Timothy Cain is the main antagonist in the 2004 film Resident Evil: Apocalypse. Cain, as he is also called, is a retired US Army Major who went on to become a high-ranking employee of the Umbrella Corporation.

  5. Major Timothy Cain is the main antagonist of Resident Evil: Apocalypse. A high-ranking member of the Umbrella Corporation's military, the Umbrella Biohazard Countermeasures Services, or U.B.C.S., Cain is placed in charge of the quarantine of Raccoon City when word of The Hive being reopened and...

  6. Dr. Alexander Isaacs is a fictional character of the Resident Evil film franchise who appeared as the main antagonist in the series. He served as a minor antagonist in Resident Evil: Apocalypse and the main antagonist in the Resident Evil: Extinction and Resident Evil: The Final Chapter.

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  8. Timothy Cain is a fictional character of the Resident Evil film series who appeared as the main antagonist in Resident Evil: Apocalypse.

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