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Sep 29, 2022 · Due to the nonspecific neonatal presentation for sepsis and the high risk of mortality and morbidity without treatment, many asymptomatic neonates undergo a sepsis workup if risk factors are present and/or clinically indicated.
- Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
- 2022/09/29
Oct 18, 2023 · Sepsis is an important cause of morbidity and mortality among newborn infants. Although the incidence of sepsis in term and late preterm neonates is low, the potential for serious adverse outcomes is of such great consequence that caregivers should have a low threshold for evaluation and treatment for possible sepsis in neonates.
Most cases are caused by group B streptococcus (GBS) and gram-negative enteric organisms (predominantly Escherichia coli). Vaginal or rectal cultures of women at term may show GBS colonization rates of up to 35%. At least 35% of their infants also become colonized.
Mar 29, 2015 · The primary reason is that the clinical presentation of neonatal infection may be subtle and nonspecific, and may overlap with noninfectious causes. 7, 8 Many clinicians empirically start broad spectrum antimicrobial regimen for infants considered at risk for sepsis but antibiotics are occasionally continued despite a negative blood culture.
- Roberto Parulan Santos, Debra Tristram
- 10.1016/j.pcl.2014.11.010
- 2015
- 2015/04
Dec 1, 2018 · Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Karen M. Puopolo, MD; William E. Benitz, MD; Theoklis E. Zaoutis, MD; COMMITTEE ON FETUS AND NEWBORN; COMMITTEE ON INFECTIOUS DISEASES; James Cummings, MD; Sandra Juul, MD; Ivan Hand, MD; Eric Eichenwald, MD; Brenda Poindexter, MD;
- Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
- 2018
Sep 29, 2022 · Due to the nonspecific neonatal presentation for sepsis and the high risk of mortality and morbidity without treatment, many asymptomatic neonates undergo a sepsis workup if risk factors are present and/or clinically indicated.
Neonatal sepsis is a clinical syndrome characterized by non-specific signs and symptoms caused by invasion by pathogens 1, 2. Sepsis is deemed culture-proven if confirmed by microbial growth on blood cultures or other sterile bodily fluids.
