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  1. In 1715, after the Calvert family had renounced Catholicism and embraced Anglicanism, the colony reverted back to a proprietary form of government. United States - Colonization, Revolution, Constitution: When Columbus arrived, he found the New World inhabited by peoples who in all likelihood had originally come from the continent of Asia.

  2. Jul 21, 2020 · Co-cultivation. It is quite typical to find multiple species of Streptomyces in traditional medical preparations such as soil or moonmilk [ 50, 54, 64 ]. Now, it has been discovered that competition and collaboration between Streptomyces and other species can also awaken silent antibiotic-synthesis clusters [ 65 ].

  3. Ancient India. The first references to tuberculosis in non-European civilization is found in the Vedas. The oldest of them ( Rigveda, 1500 BC) calls the disease yaksma. [13] The Atharvaveda calls it balasa. It is in the Atharvaveda that the first description of scrofula is given. [14]

  4. Sep 1, 2011 · Between 1944 and 1948, the United States Veterans Administration carried out extensive clinical trials in thousands of patients treated in Veterans Hospitals. A review of these trials found that streptomycin could temporarily stop the growth of TB but did not offer a permanent cure.

  5. www.merck.com › company-overview › historyHistory - Merck.com

    Funded the discovery of and distributed breakthrough antibiotic streptomycin. Tuberculosis was historically a leading cause of death in the U.S. In 1943, Dr. Selman Waksman and Albert Schatz discovered streptomycin, the first effective treatment for the disease. Merck supported Dr. Waksman's research lab and held the new drug's patent rights.

  6. www.msd.com › company-overview › historyHistory - MSD

    Tuberculosis was historically a leading cause of death in the U.S. In 1943, Dr. Selman Waksman and Albert Schatz discovered streptomycin, the first effective treatment for the disease. The company had supported Dr. Waksman’s research lab and held the patent rights.

  7. The evolution of clinical research traverses a long and fascinating journey. The recorded history of clinical trials goes back to the biblical descriptions in 500 BC. The journey moves from dietary therapy – legumes and lemons – to drugs. After basic approach of clinical trial was described in 18th century, the efforts were made to refine ...

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