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Drug eruptions are generally classified as “simple” or “complex,” referring to the risk of morbidity and mortality associated with the specific eruption. Simple morbilliform or maculopapular drug eruptions involve an exanthem, usually appear in the second week of medication therapy, and have no associated constitutional symptoms or ...
Medications can also cause pruritus and dysesthesia without an obvious eruption. A drug-induced reaction should be considered in any patient who is taking medications and who suddenly develops a symmetric cutaneous eruption. Morbilliform eruption localized to striae has been described with clindamycin.
Mar 4, 2022 · Morbilliform eruption with a recent drug history. A drug history is important to obtain in any patient with a morbilliform eruption. A comprehensive list of all medications, including over-the-counter medications and supplements, taken with start dates of each is needed to determine probable culprit drugs.
Jul 7, 2022 · The eruption often resolves, especially if the individual is being treated with antihistamines. Most authorities believe that exanthematous drug eruptions are not a precursor to severe reactions, such as TEN. Nevertheless, all patients with severe morbilliform eruptions should be monitored for mucous membrane lesions, blistering, and skin ...
Nov 16, 2021 · A fixed drug eruption: the rash comes and goes on exposure to the drug, the same body site is affected every time. The lesion(s) is a well-demarcated erythematous plaque that may blister, tending to heal with post-inflammatory hyperpigmentation ; Are there any blisters? ACDR can cause a number of blistering eruptions including:
Some morbilliform eruptions do not recur when the patient is re-exposed to the causative drug. Many antibiotics cause morbilliform eruptions. A morbilliform rash usually starts within 7–14 days of starting a new antibiotic, and lasts for 5–10 days. It may occur more quickly on re-exposure to the same drug.
The most common type of eruption is a morbilliform (resembling measles) or erythematous rash (approximately 90% of cases). Less commonly, the appearance may also be urticarial, papulosquamous, pustular, purpuric, bullous (with blisters) or lichenoid. Angioedema can also be drug-induced (most notably, by angiotensin converting enzyme inhibitors).
